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Ganoderma immunomodulatory proteins: mushrooming functional FIPs.
Lin J, Chen H, Bai Y, Li S, Liang G, Fan T, Gao N, Wu X, Li H, Chen G, Gao Y, Fan J.
Appl Microbiol Biotechnol. 2022 Apr;106(7):2367-2380. doi: 10.1007/s00253-022-11839-9. Epub 2022 Mar 29.

The medicinal mushroom Ganoderma lucidum attenuates UV-induced skin carcinogenesis and immunosuppression.
Shahid A, Huang M, Liu M, Shamim MA, Parsa C, Orlando R, Huang Y.
PLoS One. 2022 Mar 21;17(3):e0265615. doi: 10.1371/journal.pone.0265615. eCollection 2022.

Time-dependent dual beneficial modulation of interferon-γ, interleukin 5, and Treg cytokines in asthma patient peripheral blood mononuclear cells by ganoderic acid B.
Liu C, Cao M, Yang N, Reid-Adam J, Tversky J, Zhan J, Li XM.
Phytother Res. 2022 Mar;36(3):1231-1240. doi: 10.1002/ptr.7266. Epub 2022 Feb 3.

Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Li Y, Li M, Wang R, Wang B, Athari SS, Wang J.
Respir Physiol Neurobiol. 2022 May;299:103843. doi: 10.1016/j.resp.2022.103843. Epub 2022 Jan 10.

Outdoor Mold and Respiratory Health: State of Science of Epidemiological Studies.
Caillaud D, Keirsbulck M, Leger C, Leynaert B; of the Outdoor Mould ANSES Working Group.
J Allergy Clin Immunol Pract. 2022 Mar;10(3):768-784.e3. doi: 10.1016/j.jaip.2021.09.042. Epub 2021 Oct 11.

Metagenomic characterization of indoor dust fungal associated with allergy and lung inflammation among school children.
Isa KNM, Jalaludin J, Elias SM, Than LTL, Jabbar MA, Saudi ASM, Norbäck D, Hashim JH, Hashim Z.
Ecotoxicol Environ Saf. 2021 Sep 15;221:112430. doi: 10.1016/j.ecoenv.2021.112430. Epub 2021 Jun 17.

Ganoderma lucidum stimulates autophagy-dependent longevity pathways in Caenorhabditis elegans and human cells.
Peng HH, Wu CY, Hsiao YC, Martel J, Ke PY, Chiu CY, Liau JC, Chang IT, Su YH, Ko YF, Young JD, Ojcius DM.
Aging (Albany NY). 2021 May 20;13(10):13474-13495. doi: 10.18632/aging.203068. Epub 2021 May 20.

Effects of fungal beta-glucans on health - a systematic review of randomized controlled trials.
Vlassopoulou M, Yannakoulia M, Pletsa V, Zervakis GI, Kyriacou A.
Food Funct. 2021 Apr 26;12(8):3366-3380. doi: 10.1039/d1fo00122a.

New advances and potentials of fungal immunomodulatory proteins for therapeutic purposes.
Ejike UC, Chan CJ, Okechukwu PN, Lim RLH.
Crit Rev Biotechnol. 2020 Dec;40(8):1172-1190. doi: 10.1080/07388551.2020.1808581. Epub 2020 Aug 28.

A recombinant protein rLZ-8, originally extracted from Ganoderma lucidum, ameliorates OVA-induced lung inflammation by regulating Th17/Treg balance.
Liu H, Qiu F, Wang Y, Liang F, Liang J, Lin C, Liang J, Gong B, Chan S, De Zhang Z, Lai X, Hou S, Dai Z.
J Leukoc Biol. 2020 Aug;108(2):531-545. doi: 10.1002/JLB.5MA0420-453R. Epub 2020 Jun 24.

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
Wong JH, Ng TB, Chan HHL, Liu Q, Man GCW, Zhang CZ, Guan S, Ng CCW, Fang EF, Wang H, Liu F, Ye X, Rolka K, Naude R, Zhao S, Sha O, Li C, Xia L.
Appl Microbiol Biotechnol. 2020 Jun;104(11):4675-4703. doi: 10.1007/s00253-020-10476-4. Epub 2020 Apr 9.

Roles of the Skn7 response regulator in stress resistance, cell wall integrity and GA biosynthesis in Ganoderma lucidum.
Wang S, Shi L, Hu Y, Liu R, Ren A, Zhu J, Zhao M.
Fungal Genet Biol. 2018 Mar 7;114:12-23. doi: 10.1016/j.fgb.2018.03.002.

The mitogen-activated protein kinase GlSlt2 regulates fungal growth, fruiting body development, cell wall integrity, oxidative stress and ganoderic acid biosynthesis in Ganoderma lucidum.
Zhang G, Sun Z, Ren A, Shi L, Shi D, Li X, Zhao M.
Fungal Genet Biol. 2017 Jul;104:6-15. doi: 10.1016/j.fgb.2017.04.004. Epub 2017 Apr 18.

Serological Reactivity and Identification of Immunoglobulin E-Binding Polypeptides of Ganoderma applanatum Crude Spore Cytoplasmic Extract in Puerto Rican Subjects.
Vilá-Héreter F, Rivera-Mariani FE, Bolaños-Rosero B.
Int Arch Allergy Immunol. 2017;172(3):139-149. doi: 10.1159/000455254. Epub 2017 Apr 6.

Toxicology and immunology of Ganoderma lucidum polysaccharides in Kunming mice and Wistar rats.
Zhang J, Gao X, Pan Y, Xu N, Jia L.
Int J Biol Macromol. 2016 Apr;85:302-10. doi: 10.1016/j.ijbiomac.2015.12.090. Epub 2016 Jan 4.

Development of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) polysaccharides injection formulation.
Jiang Y, He A, Liu Y, Xie B, Li Y, Deng Y, Liu X, Liu Q.
Int J Med Mushrooms. 2014;16(5):411-9.

Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum.
Bhardwaj N, Katyal P, Sharma AK.
Appl Microbiol Biotechnol. 2014 Jul;98(13):5967-75. doi: 10.1007/s00253-014-5539-4. Epub 2014 Feb 28.

Production and functional characterization of a novel fungal immunomodulatory protein FIP-SN15 shuffled from two genes of Ganoderma species.
Cong WR, Xu H, Liu Y, Li QZ, Li W, Zhou XW.
Appl Microbiol Biotechnol. 2014 Jul;98(13):5967-75. doi: 10.1007/s00253-014-5539-4. Epub 2014 Feb 28.

Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen.
Jan RH, Lin TY, Hsu YC, Lee SS, Lo SY, Chang M, Chen LK, Lin YL.
BMC Immunol. 2011 May 25;12:31.

Associations between atmospheric concentrations of spores and emergency department visits for asthma among children living in Montreal.
Raphoz M, Goldberg MS, Garneau M, Héguy L, Valois MF, Guay F.
Arch Environ Occup Health. 2010 Oct-Dec;65(4):201-10.

Heterologous expression of the immunomodulatory protein gene from Ganoderma sinense in the basidiomycete Coprinopsis cinerea.
Han F, Liu Y, Guo LQ, Zeng XL, Liu ZM, Lin JF.
J Appl Microbiol. 2010 Jul 2.

Optimization of alkaline extraction of polysaccharides from Ganoderma lucidum and their effect on immune function in mice.
Huang SQ, Li JW, Wang Z, Pan HX, Chen JX, Ning ZX.
Molecules. 2010 May 25;15(5):3694-708

The effects of meteorological factors on the occurrence of Ganoderma sp. spores in the air.
Grinn-Gofroń A, Strzelczak A.
Int J Biometeorol. 2010 May 29.

Extraction of polysaccharide from Ganoderma lucidum and its immune enhancement activity.
Huang SQ, Ning ZX.
Int J Biol Macromol. 2010 Oct 1;47(3):336-41.

Safety and tolerability of an antiasthma herbal Formula (ASHMI) in adult subjects with asthma: a randomized, double-blinded, placebo-controlled, dose-escalation phase I study.
Kelly-Pieper K, Patil SP, Busse P, Yang N, Sampson H, Li XM, Wisnivesky JP, Kattan M.
J Altern Complement Med. 2009 Jul;15(7):735-43

The immune effects of edible fungus polysaccharides compounds in mice.
Yin Y, Fu W, Fu M, He G, Traore L.
Asia Pac J Clin Nutr. 2007;16 Suppl 1:258-60

Effects of triterpenoid-rich extracts of Ganoderma tsugae on airway hyperreactivity and Th2 responses in vivo.
Chen ML, Lin BF.
Int Arch Allergy Immunol. 2007;143(1):21-30.

Ganoderma tsugae in vivo modulates Th1/Th2 and macrophage responses in an allergic murine model.
Lin JY, Chen ML, Lin BF.
Food Chem Toxicol. 2006 Dec;44(12):2025-32.

Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model.
Lin JY, Chen ML, Chiang BL, Lin BF.
Int Immunopharmacol. 2006 Feb;6(2):241-51.

[Application of flow cytometry on functional assessment of health food]
Yang XF, Huang Q, Huang JM, Li Z, Cai M, Huang JK, Chen BF.
Zhonghua Yu Fang Yi Xue Za Zhi. 2005 Sep;39(5):335-41.

Effectiveness of Dp2 nasal therapy for Dp2- induced airway inflammation in mice: using oral Ganoderma lucidum as an immunomodulator.
Liu YH, Tsai CF, Kao MC, Lai YL, Tsai JJ.
J Microbiol Immunol Infect. 2003 Dec;36(4):236-42.

Common environmental allergens causing respiratory allergy in India.
Singh AB, Kumar P.
Indian J Pediatr. 2002 Mar;69(3):245-50.

Cytotoxicity and immunogenicity of SACCHACHITIN and its mechanism of action on skin wound healing.
Hung WS, Fang CL, Su CH, Lai WF, Chang YC, Tsai YH.
J Biomed Mater Res. 2001 Jul;56(1):93-100.

Ganoderma lucidum: partial characterization of spore and whole body antigenic extracts.
Gupta SK, Pereira BM, Singh AB.
J Investig Allergol Clin Immunol. 2000 Mar-Apr;10(2):83-9.

Fungal spore concentrations in the atmosphere at the Anatolia quarter of Istanbul, Turkey.
Colakoğlu G.
J Basic Microbiol. 1996;36(3):155-62.

Sensitization to Ganoderma lucidum in patients with respiratory allergy in India.
Singh AB, Gupta SK, Pereira BM, Prakash D.
Clin Exp Allergy. 1995 May;25(5):440-7

[Current aspects of fungal spores allergy]
Helbling A, Reese G, Horner WE, Lehrer SB.
Schweiz Med Wochenschr. 1994 May 28;124(21):885-92.

Basidiomycete allergens: comparison of three Ganoderma species.
Horner WE, Helbling A, Lehrer SB.
Allergy. 1993 Feb;48(2):110-6

The basidiomycete ganoderma and asthma: collection, quantitation and immunogenicity of the spores.
Cutten AE, Hasnain SM, Segedin BP, Bai TR, McKay EJ.
N Z Med J. 1988 Jun 8;101(847 Pt 1):361-3.

[Studies on Ganoderma lucidum. VII. Anti-allergic effect. (2)]
Nogami M, Ito M, Kubo M, Takahashi M, Kimura H, Matsuike Y.
Yakugaku Zasshi. 1986 Jul;106(7):600-4.

Human sensitization to Ganoderma antigen.
Tarlo SM, Bell B, Srinivasan J, Dolovich J, Hargreave FE.
J Allergy Clin Immunol. 1979 Jul;64(1):43-9.

Effect of polysaccharides from Ganoderma applanatum on immune responses. I. Enhancing effect on the induction of delayed hypersensitivity in mice.
Nakashima S, Umeda Y, Kanada T.
Microbiol Immunol. 1979;23(6):501-13.

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