図書館 論文紹介
癌・免疫 血糖 血圧 肝臓 脂質代謝
鎮痛 老化・美容 アレルギー 炎症  

G. sinense and P. notoginseng Extracts Improve Healthspan of Aging Flies and Provide Protection in A Huntington Disease Model.
Teseo S, Houot B, Yang K, Monnier V, Liu G, Tricoire H.
Aging Dis. 2021 Apr 1;12(2):425-440. doi: 10.14336/AD.2020.0714-1. eCollection 2021 Apr.

Ganoderma lucidum Rhodiola compound preparation prevent D-galactose-induced immune impairment and oxidative stress in aging rat model.
Yuan S, Yang Y, Li J, Tan X, Cao Y, Li S, Hong HD, Liu L, Zhang Q.
Sci Rep. 2020 Nov 6;10(1):19244. doi: 10.1038/s41598-020-76249-1.

The effect of Ganoderma lucidum spore oil in early skin wound healing: interactions of skin microbiota and inflammation.
Jiao C, Xie Y, Yun H, Liang H, He C, Jiang A, Wu Q, Yang BB.
Aging (Albany NY). 2020 Jul 21;12(14):14125-14140. doi: 10.18632/aging.103412. Epub 2020 Jul 21.

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
Wong JH, Ng TB, Chan HHL, Liu Q, Man GCW, Zhang CZ, Guan S, Ng CCW, Fang EF, Wang H, Liu F, Ye X, Rolka K, Naude R, Zhao S, Sha O, Li C, Xia L.
Appl Microbiol Biotechnol. 2020 Jun;104(11):4675-4703. doi: 10.1007/s00253-020-10476-4. Epub 2020 Apr 9.

Herbal Medicine for Slowing Aging and Aging-associated Conditions: Efficacy, Mechanisms and Safety.
Phu HT, Thuan DTB, Nguyen THD, Posadino AM, Eid AH, Pintus G.
Curr Vasc Pharmacol. 2020;18(4):369-393. doi: 10.2174/1570161117666190715121939.

GCN4 regulates secondary metabolism through activating antioxidant genes expression under nitrogen limitation in Ganoderma lucidum.
Lian L, Wang L, Song S, Zhu J, Liu R, Shi L, Ren A, Zhao M.
Appl Environ Microbiol. 2021 May 7:AEM.00156-21. doi: 10.1128/AEM.00156-21. Online ahead of print.

Fungi and Fungal Metabolites for the Improvement of Human and Animal Nutrition and Health.
Dufossé L, Fouillaud M, Caro Y.
J Fungi (Basel). 2021 Apr 4;7(4):274. doi: 10.3390/jof7040274.

Structural characterization and amelioration of sulfated polysaccharides from Ganoderma applanatum residue against CCl(4)-induced hepatotoxicity.
Song X, Cui W, Gao Z, Zhang J, Jia L.
Int Immunopharmacol. 2021 Mar 31;96:107554. doi: 10.1016/j.intimp.2021.107554. Online ahead of print.

PLGA nanoparticles containing Lingzhi extracts rescue corneal epithelial cells from oxidative damage.
Tsai IL, Tsai CY, Kuo LL, Woung LC, Ku RY, Cheng YH.
Exp Eye Res. 2021 May;206:108539. doi: 10.1016/j.exer.2021.108539. Epub 2021 Mar 17.

Production, characterization, and bioactivities of exopolysaccharides from the submerged culture of Ganoderma cantharelloideum M. H. Liu.
Long Z, Xue Y, Ning Z, Sun J, Li J, Su Z, Liu Q, Xu C, Yan JK.
3 Biotech. 2021 Mar;11(3):145. doi: 10.1007/s13205-021-02696-w. Epub 2021 Feb 26.

Effect of the heme oxygenase gene on mycelial growth and polysaccharide synthesis in Ganoderma lucidum.
Wang T, Wang Y, Chen C, Ren A, Yu H, Zhao M.
J Basic Microbiol. 2021 Mar;61(3):253-264. doi: 10.1002/jobm.202000622. Epub 2021 Feb 5.

Characterization and Hepatoprotections of Ganoderma lucidum Polysaccharides against Multiple Organ Dysfunction Syndrome in Mice.
Zhang Y, Feng Y, Wang W, Jia L, Zhang J.
Oxid Med Cell Longev. 2021 Feb 3;2021:9703682. doi: 10.1155/2021/9703682. eCollection 2021.

Impact of olive mill wastewaters on the physiological behavior of a wild-type new Ganoderma resinaceum isolate.
Diamantopoulou P, Gardeli C, Papanikolaou S.
Environ Sci Pollut Res Int. 2021 Apr;28(16):20570-20585. doi: 10.1007/s11356-020-11835-4. Epub 2021 Jan 6.

Effects of redox interference on the pancreatic mitochondria and the abnormal blood glucose.
Xie F, Wu M, Lai B, Halim M, Liu S, Shi D.
Free Radic Res. 2021 Jan 4:1-12. doi: 10.1080/10715762.2020.1866180. Online ahead of print.

Biological Activities of Different Strains of the Genus Ganoderma spp. (Agaricomycetes) from Mexico.
Espinosa-García V, Mendoza G, Shnyreva AV, Padrón JM, Trigos Á.
Int J Med Mushrooms. 2021;23(2):67-77. doi: 10.1615/IntJMedMushrooms.2021037451.

Optimization of ultrasonic-assisted extraction of polysaccharides and triterpenoids from the medicinal mushroom Ganoderma lucidum and evaluation of their in vitro antioxidant capacities.
Zheng S, Zhang W, Liu S.
PLoS One. 2020 Dec 31;15(12):e0244749. doi: 10.1371/journal.pone.0244749. eCollection 2020.

Anti-Inflammatory, Antioxidant and Enzyme Inhibition Activities in Correlation with Mycochemical Profile of Selected Indigenous Ganoderma spp. from Balkan Region (Serbia).
Rašeta M, Popović M, Beara I, Šibul F, Zengin G, Krstić S, Karaman M.
Chem Biodivers. 2021 Feb;18(2):e2000828. doi: 10.1002/cbdv.202000828. Epub 2020 Dec 29.

Pleurotus Macrofungi-Assisted Nanoparticle Synthesis and Its Potential Applications: A Review.
Bhardwaj K, Sharma A, Tejwan N, Bhardwaj S, Bhardwaj P, Nepovimova E, Shami A, Kalia A, Kumar A, Abd-Elsalam KA, Kuča K.
J Fungi (Basel). 2020 Dec 9;6(4):351. doi: 10.3390/jof6040351.

Effect and Mechanism of Ganoderma lucidum Spores on Alleviation of Diabetic Cardiomyopathy in a Pilot in vivo Study.
Shaher F, Wang S, Qiu H, Hu Y, Zhang Y, Wang W, Al-Ward H, Abdulghani MAM, Baldi S, Zhou S.
Diabetes Metab Syndr Obes. 2020 Dec 7;13:4809-4822. doi: 10.2147/DMSO.S281527. eCollection 2020.

One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration.
Wu MH, Wang W, Chao FC, Hsieh CM, Chen LC, Lin HL, Ho HO, Huang TJ, Sheu MT.
Carbohydr Polym. 2021 Feb 15;254:117270. doi: 10.1016/j.carbpol.2020.117270. Epub 2020 Nov 7.

The Novel Herbal Cocktail AGA Alleviates Oral Cancer through Inducing Apoptosis, Inhibited Migration and Promotion of Cell Cycle Arrest at SubG1 Phase.
Lu JH, Chou YR, Deng YH, Huang MS, Chien ST, Quynh BTN, Wu CY, Peláez Achtmann EA, Cheng HC, Dubey NK, Deng WP.
Cancers (Basel). 2020 Oct 31;12(11):3214. doi: 10.3390/cancers12113214.

Comparison of physicochemical and biochemical properties of natural and arginine-modified melanin from medicinal mushroom Ganoderma lucidum.
Xu L, Li J, Chang M, Cheng Y, Geng X, Meng J, Zhu M.
J Basic Microbiol. 2020 Nov;60(11-12):1014-1028. doi: 10.1002/jobm.202000430. Epub 2020 Oct 26.

Isolation, structural characterization, and biological activities of galactomannans from Rhizopogon luteolus and Ganoderma adspersum mushrooms.
Tel-Çayan G, Muhammad A, Deveci E, Duru ME, Öztürk M.
Int J Biol Macromol. 2020 Dec 15;165(Pt B):2395-2403. doi: 10.1016/j.ijbiomac.2020.10.040. Epub 2020 Oct 13.

Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials.
Grammatikopoulou MG, Gkiouras K, Papageorgiou SΤ, Myrogiannis I, Mykoniatis I, Papamitsou T, Bogdanos DP, Goulis DG.
Nutrients. 2020 Sep 29;12(10):2985. doi: 10.3390/nu12102985.

Natural compounds against doxorubicin-induced cardiotoxicity: A review on the involvement of Nrf2/ARE signaling pathway.
Yarmohammadi F, Rezaee R, Karimi G.
Phytother Res. 2021 Mar;35(3):1163-1175. doi: 10.1002/ptr.6882. Epub 2020 Sep 28.
Ganoderma Lucidum from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat Model.
Oluwafemi Adetuyi B, Olamide Okeowo T, Adefunke Adetuyi O, Abraham Adebisi O, Ogunlana OO, Janet Oretade O, Marraiki N, Beshbishy AM, N Welson N, Batiha GE.
Biology (Basel). 2020 Sep 27;9(10):313. doi: 10.3390/biology9100313.

Ganoderma lucidum inspired silver nanoparticles and its biomedical applications with special reference to drug resistant Escherichia coli isolates from CAUTI.
Al-Ansari MM, Dhasarathan P, Ranjitsingh AJA, Al-Humaid LA.
Saudi J Biol Sci. 2020 Nov;27(11):2993-3002. doi: 10.1016/j.sjbs.2020.09.008. Epub 2020 Sep 10.

Protective effects of curcumin and Ganoderma lucidum on hippocampal damage caused by the organophosphate insecticide chlorpyrifos in the developing rat brain: Stereological, histopathological and immunohistochemical study.
Eronat K, Sağır D.
Acta Histochem. 2020 Oct;122(7):151621. doi: 10.1016/j.acthis.2020.151621. Epub 2020 Sep 9.

Ganoderma lucidum Ethanol Extracts Enhance Re-Epithelialization and Prevent Keratinocytes from Free-Radical Injury.
Abate M, Pepe G, Randino R, Pisanti S, Basilicata MG, Covelli V, Bifulco M, Cabri W, D'Ursi AM, Campiglia P, Rodriquez M.
Pharmaceuticals (Basel). 2020 Aug 29;13(9):224. doi: 10.3390/ph13090224.

In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells.
Lau MF, Chua KH, Sabaratnam V, Kuppusamy UR.
Biotechnol Appl Biochem. 2020 Aug 28. doi: 10.1002/bab.2013. Online ahead of print.

Evaluation of the protective effects of Ganoderma applanatum against doxorubicin-induced toxicity in Dalton's Lymphoma Ascites (DLA) bearing mice.
Lalmuansangi C, Zosangzuali M, Lalremruati M, Tochhawng L, Siama Z.
Drug Chem Toxicol. 2020 Aug 28:1-11. doi: 10.1080/01480545.2020.1812630. Online ahead of print.

Effects of co-administration of Ganoderma terpenoid extract with chloroquine on inflammatory markers and antioxidant status in Plasmodium berghei-infected mice.
Oluba OM, Akpor OB, Adebiyi FD, Josiah SJ, Alabi OO, Shoyombo AO, Olusola AO.
J Integr Med. 2020 Nov;18(6):522-529. doi: 10.1016/j.joim.2020.08.002. Epub 2020 Aug 13.

Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum.
Yuan S, Pan Y, Zhang Z, He Y, Teng Y, Liang H, Wu X, Yang H, Zhou P.
Biol Pharm Bull. 2020 Oct 1;43(10):1542-1550. doi: 10.1248/bpb.b20-00358. Epub 2020 Aug 5.

Enhanced exopolysaccharide production in submerged fermentation of Ganoderma lucidum by Tween 80 supplementation.
Yang X, Yang Y, Zhang Y, He J, Xie Y.
Bioprocess Biosyst Eng. 2021 Jan;44(1):47-56. doi: 10.1007/s00449-020-02418-1. Epub 2020 Aug 2.

Ganoderma lucidum Ameliorates Neurobehavioral Changes and Oxidative Stress Induced by Ethanol Binge Drinking.
Nascimento CP, Luz DA, da Silva CCS, Malcher CMR, Fernandes LMP, Dalla Santa HS, Gomes ARQ, Monteiro MC, Ribeiro CHMA, Fontes-Júnior EA, Maia CSF.
Oxid Med Cell Longev. 2020 Jul 30;2020:2497845. doi: 10.1155/2020/2497845. eCollection 2020.

Associated Targets of the Antioxidant Cardioprotection of Ganoderma lucidum in Diabetic Cardiomyopathy by Using Open Targets Platform: A Systematic Review.
Shaher F, Qiu H, Wang S, Hu Y, Wang W, Zhang Y, Wei Y, Al-Ward H, Abdulghani MAM, Alenezi SK, Baldi S, Zhou S.
Biomed Res Int. 2020 Jul 25;2020:7136075. doi: 10.1155/2020/7136075. eCollection 2020.

Optimization of antioxidant, anti-diabetic, and anti-inflammatory activities and ganoderic acid content of differentially dried Ganoderma lucidum using response surface methodology.
Ryu DH, Cho JY, Sadiq NB, Kim JC, Lee B, Hamayun M, Lee TS, Kim HS, Park SH, Nho CW, Kim HY.
Food Chem. 2021 Jan 15;335:127645. doi: 10.1016/j.foodchem.2020.127645. Epub 2020 Jul 25.

Ganoderma lucidum Prevents Cisplatin-Induced Nephrotoxicity through Inhibition of Epidermal Growth Factor Receptor Signaling and Autophagy-Mediated Apoptosis.
Mahran YF, Hassan HM.
Oxid Med Cell Longev. 2020 Jul 6;2020:4932587. doi: 10.1155/2020/4932587. eCollection 2020.

Antioxidant, Cytotoxic and Antimicrobial Activity of Chitosan Preparations Extracted from Ganoderma Lucidum Mushroom.
Savin S, Craciunescu O, Oancea A, Ilie D, Ciucan T, Antohi LS, Toma A, Nicolescu A, Deleanu C, Oancea F.
Chem Biodivers. 2020 Jul;17(7):e2000175. doi: 10.1002/cbdv.202000175. Epub 2020 Jun 5.

Ganoderma lucidum: A rational pharmacological approach to surmount cancer.
Ahmad MF.
J Ethnopharmacol. 2020 Oct 5;260:113047. doi: 10.1016/j.jep.2020.113047. Epub 2020 Jun 3.

Extraction of triterpenoid compounds from Ganoderma Lucidum spore powder through a dual-mode sonication process.
Shen SF, Zhu LF, Wu Z, Wang G, Ahmad Z, Chang MW.
Drug Dev Ind Pharm. 2020 Jun;46(6):963-974. doi: 10.1080/03639045.2020.1764022. Epub 2020 May 13.

Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety.
Shaito A, Thuan DTB, Phu HT, Nguyen THD, Hasan H, Halabi S, Abdelhady S, Nasrallah GK, Eid AH, Pintus G.
Front Pharmacol. 2020 Apr 7;11:422. doi: 10.3389/fphar.2020.00422. eCollection 2020.

Ganoderma lucidum Triterpenoids (GLTs) Reduce Neuronal Apoptosis via Inhibition of ROCK Signal Pathway in APP/PS1 Transgenic Alzheimer's Disease Mice.
Yu N, Huang Y, Jiang Y, Zou L, Liu X, Liu S, Chen F, Luo J, Zhu Y.
Oxid Med Cell Longev. 2020 Jan 28;2020:9894037. doi: 10.1155/2020/9894037. eCollection 2020.

Effect of Cultured Substrates on the Chemical Composition and Biological Activities of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Song T, Zhang Z, Liu S, Chen J, Cai W.
Int J Med Mushrooms. 2020;22(12):1183-1190. doi: 10.1615/IntJMedMushrooms.2020037133.

Comparative Study on Bioactivities from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Gives an Insight into the Fermentation Broth Showing Greater Antioxidative Activities.
Xie C, Tang P, Yan S, Yang Q, Zhang Z, Gong W, Zhu Z, Zhou Y, Yan L, Hu Z, Wang X, Peng Y.
Int J Med Mushrooms. 2020;22(7):627-639. doi: 10.1615/IntJMedMushrooms.2020035042.

Effects of Extraction Temperature on Efficacy of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Aqueous Extract against Oxidative Stress.
Tulsawani R, Sharma P, Manimaran M, Koganti P, Singh M, Meena DK, Negi PS, Misra K.
Int J Med Mushrooms. 2020;22(6):547-558. doi: 10.1615/IntJMedMushrooms.2020035074.

Bioactivities and Molecular Characterizations of the Polysaccharide(s) from Ultrasonic-Circulating Extracts of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).
Chen TQ, Kan YJ, Yang C, Wu JG, Wu JZ.
Int J Med Mushrooms. 2020;22(5):455-466. doi: 10.1615/IntJMedMushrooms.2020034227.

Effect of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Capsules on Colistin-Induced Nephrotoxicity.
Talih G, Kantekin ÇÜ, Göçmen Y, Çelik S, Talih T, Esmaoğlu A.
Int J Med Mushrooms. 2020;22(5):445-453. doi: 10.1615/IntJMedMushrooms.2020034229.

Antioxidant Activities of Selected Medicinal Mushroom Submerged Cultivated Mycelia.
Liu YM, Lai YH, Hsieh FM, Chiu YM, Wasser SP, Mau JL.
Int J Med Mushrooms. 2020;22(4):367-377. doi: 10.1615/IntJMedMushrooms.2020034161.

Ganoderma lucidum Polysaccharide Enzymatic Hydrolysate Suppresses the Growth of Human Colon Cancer Cells via Inducing Apoptosis.
Bai JH, Xu J, Zhao J, Zhang R.
Cell Transplant. 2020 Jan-Dec;29:963689720931435. doi: 10.1177/0963689720931435.

Comparative Studies on Bioactive Compounds, Ganoderic Acid Biosynthesis, and Antioxidant Activity of Pileus and Stipes of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) Fruiting Body at Different Growth Stages.
Ren X, Wang J, Huang L, Cheng K, Zhang M, Yang H.
Int J Med Mushrooms. 2020;22(2):133-144. doi: 10.1615/IntJMedMushrooms.2020033683.

Deacetyl Ganoderic Acid F Inhibits LPS-Induced Neural Inflammation via NF-κB Pathway Both In Vitro and In Vivo.
Sheng F, Zhang L, Wang S, Yang L, Li P.
Nutrients. 2019 Dec 27;12(1):85. doi: 10.3390/nu12010085.

Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness.
Pan Y, Lin Z.
Adv Exp Med Biol. 2019;1182:299-309. doi: 10.1007/978-981-32-9421-9_13. Review.

Herbal Medicine for Slowing Aging and Aging-Associated Conditions: Efficacy, Mechanisms, and Safety.
Phu HT, Thuan DTB, Nguyen THD, Posadino AM, Eid AH, Pintus G.
Curr Vasc Pharmacol. 2019 Jul 15. doi: 10.2174/1570161117666190715121939. [Epub ahead of print]

Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
Lai G, Guo Y, Chen D, Tang X, Shuai O, Yong T, Wang D, Xiao C, Zhou G, Xie Y, Yang BB, Wu Q.
Front Pharmacol. 2019 Mar 26;10:272. doi: 10.3389/fphar.2019.00272. eCollection 2019.

Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway.
Li HN, Zhao LL, Zhou DY, Chen DQ.
Med Sci Monit. 2020 Apr 4;26:e921905. doi: 10.12659/MSM.921905.

Rutin protects boar sperm from cryodamage via enhancing the antioxidative defense.
Xu D, Wu L, Yang L, Liu D, Chen H, Geng G, Li Q.
Anim Sci J. 2020 Jan;91(1):e13328. doi: 10.1111/asj.13328.

The protective effect of Ganoderma lucidum on testicular torsion/detorsion-induced ischemia-reperfusion (I/R) injury.
Doğan G, İpek H.
Acta Cir Bras. 2020 Mar 20;35(1):e202000103. doi: 10.1590/s0102-865020200010000003. eCollection 2020.

Effects of sporoderm-broken spores of Ganoderma lucidum on growth performance, antioxidant function and immune response of broilers.
Liu T, Zhou J, Li W, Rong X, Gao Y, Zhao L, Fan Y, Zhang J, Ji C, Ma Q.
Anim Nutr. 2020 Mar;6(1):39-46. doi: 10.1016/j.aninu.2019.11.005. Epub 2019 Dec 23.

Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review.
Lu J, He R, Sun P, Zhang F, Linhardt RJ, Zhang A.
Int J Biol Macromol. 2020 May 1;150:765-774. doi: 10.1016/j.ijbiomac.2020.02.035. Epub 2020 Feb 6. Review.

Functions of reactive oxygen species in apoptosis and ganoderic acid biosynthesis in Ganoderma lucidum.
Zhu J, Wu F, Yue S, Chen C, Song S, Wang H, Zhao M.
FEMS Microbiol Lett. 2019 Dec 1;366(23). pii: fnaa015. doi: 10.1093/femsle/fnaa015.

Ergosterol Peroxide from the Medicinal Mushroom Ganoderma lucidum Inhibits Differentiation and Lipid Accumulation of 3T3-L1 Adipocytes.
Jeong YU, Park YJ.
Int J Mol Sci. 2020 Jan 10;21(2). pii: E460. doi: 10.3390/ijms21020460.

Ganoderma carnosum and Ganoderma pfeifferi: Metal concentration, phenolic content, and biological activity.
Yalcin OU, Sarikurkcu C, Cengiz M, Gungor H, Ćavar Zeljković S.
Mycologia. 2020 Jan-Feb;112(1):1-8. doi: 10.1080/00275514.2019.1689748. Epub 2020 Jan 3.

The Effect of Mushroom Extracts on Human Platelet and Blood Coagulation: In vitro Screening of Eight Edible Species.
Poniedziałek B, Siwulski M, Wiater A, Komaniecka I, Komosa A, Gąsecka M, Magdziak Z, Mleczek M, Niedzielski P, Proch J, Ropacka-Lesiak M, Lesiak M, Henao E, Rzymski P.
Nutrients. 2019 Dec 12;11(12). pii: E3040. doi: 10.3390/nu11123040.

Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum.
Wang C, Liu X, Lian C, Ke J, Liu J.
Molecules. 2019 Nov 28;24(23). pii: E4353. doi: 10.3390/molecules24234353.

Ganoderma lucidum, a promising agent possessing antioxidant and anti-inflammatory effects for treating calvarial defects with graft application in rats.
Laçin N, İzol SB, İpek F, Tuncer MC.
Acta Cir Bras. 2019 Nov 25;34(9):e201900904. doi: 10.1590/s0102-865020190090000004. eCollection 2019.

Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Skin Diseases and Care.
Yin Z, Yang B, Ren H.
Adv Exp Med Biol. 2019;1182:311-321. doi: 10.1007/978-981-32-9421-9_14. Review.

Antioxidative and Free Radical Scavenging Activity of Ganoderma (Lingzhi).
Lin Z, Deng A.
Adv Exp Med Biol. 2019;1182:271-297. doi: 10.1007/978-981-32-9421-9_12. Review.

Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System.
Meng J, Yang B.
Adv Exp Med Biol. 2019;1182:181-199. doi: 10.1007/978-981-32-9421-9_7. Review.

Evidence for Effective Inhibitory Actions on Hyperpolarization-Activated Cation Current Caused by Ganoderma Triterpenoids, the Main Active Constitutents of Ganoderma Spores.
Chang WT, Gao ZH, Lo YC, Wu SN.
Molecules. 2019 Nov 22;24(23). pii: E4256. doi: 10.3390/molecules24234256.

Production of triterpenoid compounds from Ganoderma lucidum spore powder using ultrasound-assisted extraction.
Shen SF, Zhu LF, Wu Z, Wang G, Ahmad Z, Chang MW.
Prep Biochem Biotechnol. 2020;50(3):302-315. doi: 10.1080/10826068.2019.1692218. Epub 2019 Nov 22.

Synthesis and characterization of Reishi mushroom-mediated green synthesis of silver nanoparticles for the biochemical applications.
Aygün A, Özdemir S, Gülcan M, Cellat K, Şen F.
J Pharm Biomed Anal. 2020 Jan 30;178:112970. doi: 10.1016/j.jpba.2019.112970. Epub 2019 Nov 4.
Biovalorization of soybean residue (okara) via fermentation with Ganoderma lucidum and Lentinus edodes to attain products with high anti-osteoporotic effects.
Yang LC, Fu TJ, Yang FC.
J Biosci Bioeng. 2020 Apr;129(4):514-518. doi: 10.1016/j.jbiosc.2019.10.003. Epub 2019 Nov 7.

High Oxygen Treatments Enhance the Contents of Phenolic Compound and Ganoderic Acid, and the Antioxidant and DNA Damage Protective Activities of Ganoderma lingzhi Fruiting Body.
Dong Q, Li Y, Liu G, Zhang Z, Zhou H, Yang H.
Front Microbiol. 2019 Oct 18;10:2363. doi: 10.3389/fmicb.2019.02363. eCollection 2019.

Bioactivity-Guided Isolation of Acetylcholinesterase Inhibitor from Ganoderma mediosinense (Agaricomycetes).
Kaur A, Randhawa K, Singh V, Shri R.
Int J Med Mushrooms. 2019;21(8):755-763. doi: 10.1615/IntJMedMushrooms.2019031508.

Ganoderma proteins and their potential applications in cosmetics.
Li LD, Mao PW, Shao KD, Bai XH, Zhou XW.
Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9239-9250. doi: 10.1007/s00253-019-10171-z. Epub 2019 Oct 29. 

Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma with Ganoderma lucidum Extracts.
Huh S, Lee S, Choi SJ, Wu Z, Cho JH, Kim L, Shin YS, Kang BW, Kim JG, Liu K, Cho H, Kang H.
Molecules. 2019 Oct 24;24(21). pii: E3834. doi: 10.3390/molecules24213834.

Oregonensins A and B, new meroterpenoids from the culture broth of Ganoderma oregonense and their antioxidant activity.
Kim JY, Woo EE, Ha LS, Kim YH, Lee IK, Yun BS.
J Antibiot (Tokyo). 2020 Feb;73(2):112-115. doi: 10.1038/s41429-019-0248-y. Epub 2019 Oct 15.

Pharmacological effects of Ganoderma lucidum extract against high-altitude stressors and its subchronic toxicity assessment.
Sharma P, Tulsawani R, Agrawal U.
J Food Biochem. 2019 Dec;43(12):e13081. doi: 10.1111/jfbc.13081. Epub 2019 Oct 14.

Antigenotoxic and antioxidant potential of medicinal mushrooms (Immune Assist) against DNA damage induced by free radicals-an in vitro study.
Živković L, Bajić V, Bruić M, Borozan S, Popić K, Topalović D, Santibanez J, Spremo-Potparević B.
Mutat Res. 2019 Sep;845:403078. doi: 10.1016/j.mrgentox.2019.06.008. Epub 2019 Aug 1.

C28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity.
Shi Q, Huang Y, Su H, Gao Y, Peng X, Zhou L, Li X, Qiu M.
Phytochemistry. 2019 Dec;168:112109. doi: 10.1016/j.phytochem.2019.112109. Epub 2019 Sep 5.

Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species.
Deveci E, Çayan F, Tel-Çayan G, Duru ME.
J Food Biochem. 2019 Sep;43(9):e12965. doi: 10.1111/jfbc.12965. Epub 2019 Jul 2.

Evaluation of the protective effects of Ganoderma atrum polysaccharide on acrylamide-induced injury in small intestine tissue of rats.
Yang Y, Zhang L, Jiang G, Lei A, Yu Q, Xie J, Chen Y.
Food Funct. 2019 Sep 1;10(9):5863-5872. doi: 10.1039/c9fo01452g. Epub 2019 Aug 29.

GSP-2, a polysaccharide extracted from Ganoderma sinense, is a novel toll-like receptor 4 agonist.
Liu KS, Zhang C, Dong HL, Li KK, Han QB, Wan Y, Chen R, Yang F, Li HL, Ko CH, Han XQ.
PLoS One. 2019 Aug 23;14(8):e0221636. doi: 10.1371/journal.pone.0221636. eCollection 2019.

Use of Ganoderma Lucidum polysaccharide to control cotton fusarium wilt, and the mechanism involved.
Zhang Z, Diao H, Wang H, Wang K, Zhao M.
Pestic Biochem Physiol. 2019 Jul;158:149-155. doi: 10.1016/j.pestbp.2019.05.003. Epub 2019 May 11.

Facile Nanolization Strategy for Therapeutic Ganoderma Lucidum Spore Oil to Achieve Enhanced Protection against Radiation-Induced Heart Disease.
Dai C, He L, Ma B, Chen T.
Small. 2019 Sep;15(36):e1902642. doi: 10.1002/smll.201902642. Epub 2019 Jul 28.

The ameliorations of Ganoderma applanatum residue polysaccharides against CCl4 induced liver injury.
Gao Z, Yuan F, Li H, Feng Y, Zhang Y, Zhang C, Zhang J, Song Z, Jia L.
Int J Biol Macromol. 2019 Sep 15;137:1130-1140. doi: 10.1016/j.ijbiomac.2019.07.044. Epub 2019 Jul 8.

GPP (Composition of Ganoderma Lucidum Poly-saccharides and Polyporus Umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice.
Huang Q, Li L, Chen H, Liu Q, Wang Z.
Nutrients. 2019 Jun 28;11(7). pii: E1480. doi: 10.3390/nu11071480.

Evaluation of laccase production by Ganoderma lucidum in submerged and solid-state fermentation using different inducers.
Rodrigues EM, Karp SG, Malucelli LC, Helm CV, Alvarez TM.
J Basic Microbiol. 2019 Aug;59(8):784-791. doi: 10.1002/jobm.201900084. Epub 2019 Jul 1.

Effects of Macuprev® Supplementation in Age-Related Macular Degeneration: A Double-Blind Randomized Morpho-Functional Study Along 6 Months of Follow-Up.
Parravano M, Tedeschi M, Manca D, Costanzo E, Di Renzo A, Giorno P, Barbano L, Ziccardi L, Varano M, Parisi V.
Adv Ther. 2019 Sep;36(9):2493-2505. doi: 10.1007/s12325-019-01016-2. Epub 2019 Jun 25. Erratum in: Adv Ther. 2019 Nov;36(11):3288. 

Protective effects of Ganoderma lucidum triterpenoids on oxidative stress and apoptosis in the spleen of chickens induced by cadmium.
Teng X, Zhang W, Song Y, Wang H, Ge M, Zhang R.
Environ Sci Pollut Res Int. 2019 Aug;26(23):23967-23980. doi: 10.1007/s11356-019-05638-5. Epub 2019 Jun 20.

Interdependent nitric oxide and hydrogen peroxide independently regulate the coix seed oil-induced triterpene acid accumulation in Ganoderma lingzhi.
Liu YN, Tong T, Zhang RR, Liu LM, Shi ML, Ma YC, Liu GQ.
Mycologia. 2019 Jul-Aug;111(4):529-540. doi: 10.1080/00275514.2019.1615816. Epub 2019 Jun 3.

Characterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma lucidum.
Xu Y, Zhang X, Yan XH, Zhang JL, Wang LY, Xue H, Jiang GC, Ma XT, Liu XJ.
Int J Biol Macromol. 2019 Aug 15;135:706-716. doi: 10.1016/j.ijbiomac.2019.05.166. Epub 2019 May 23.

Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum.
Feng X, Wang Y.
Cell Mol Biol (Noisy-le-grand). 2019 Apr 30;65(4):37-42.

Ganoderma lucidum polysaccharide used for treating physical frailty in China.
Zeng P, Chen Y, Zhang L, Xing M.
Prog Mol Biol Transl Sci. 2019;163:179-219. doi: 10.1016/bs.pmbts.2019.02.009. Epub 2019 Mar 26. Review.

Ganoderma sinense polysaccharide: An adjunctive drug used for cancer treatment.
Zhang Y, Jiang Y, Zhang M, Zhang L.
Prog Mol Biol Transl Sci. 2019;163:165-177. doi: 10.1016/bs.pmbts.2019.02.008. Epub 2019 Mar 25. Review.

Kinetic identification of phenolic compounds and potential production of caffeic acid by Ganoderma lipsiense in solid-state fermentation.
Costa TM, Kaufmann V, Paganelli CJ, Siebert DA, Micke GA, Alberton MD, Tavares LBB, de Oliveira D.
Bioprocess Biosyst Eng. 2019 Aug;42(8):1325-1332. doi: 10.1007/s00449-019-02131-8. Epub 2019 Apr 26.

Optimization of Cultivation Conditions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) for the Highest Antioxidant Activity and Antioxidant Content.
Lou HW, Guo XY, Zhang XC, Guo LQ, Lin JF.
Int J Med Mushrooms. 2019;21(4):353-366. doi: 10.1615/IntJMedMushrooms.2019030338.

[Study on chemical constituents from fruiting bodies of Ganoderma australe].
Ge YZ, Ma QY, Kong FD, Xie QY, An CL, Yu ZF, Zhao YX.

Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(3):489-494. doi: 10.19540/j.cnki.cjcmm.20181121.004. Chinese.
Effect of the taxonomic group of fungi and type of substrate on the antioxidant activity of a solid-state fermentation system.

El-Katony TM, El-Dein MMN, El-Fallal AA, Ibrahim NG.
Int Microbiol. 2019 Jun;22(2):203-215. doi: 10.1007/s10123-018-00040-6. Epub 2018 Nov 9.

Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities.
Lu SY, Peng XR, Dong JR, Yan H, Kong QH, Shi QQ, Li DS, Zhou L, Li ZR, Qiu MH.
Fitoterapia. 2019 Apr;134:58-64. doi: 10.1016/j.fitote.2019.01.013. Epub 2019 Feb 11.

De novo transcriptome assembly and protein profiling of copper-induced lignocellulolytic fungus Ganoderma lucidum MDU-7 reveals genes involved in lignocellulose degradation and terpenoid biosynthetic pathways.
Jain KK, Kumar A, Shankar A, Pandey D, Chaudhary B, Sharma KK.
Genomics. 2020 Jan;112(1):184-198. doi: 10.1016/j.ygeno.2019.01.012. Epub 2019 Jan 26.

Effects of Fungal Polysaccharide on Oxidative Damage and TLR4 Pathway to the Central Immune Organs in Cadmium Intoxication in Chickens.
Li R, Zhang L, Tang Z, Li T, Li G, Zhang R, Ge M.
Biol Trace Elem Res. 2019 Oct;191(2):464-473. doi: 10.1007/s12011-018-1627-0. Epub 2019 Jan 10.

Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma.
Gill BS, Navgeet, Kumar S.
Mol Cell Biochem. 2019 Jun;456(1-2):1-14. doi: 10.1007/s11010-018-3485-7. Epub 2018 Dec 3.

Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction.
Kang Q, Chen S, Li S, Wang B, Liu X, Hao L, Lu J.
Int J Biol Macromol. 2019 Mar 1;124:1137-1144. doi: 10.1016/j.ijbiomac.2018.11.215. Epub 2018 Nov 24.

The anti-oxidation and anti-aging effects of Ganoderma lucidum in Caenorhabditis elegans.
Cuong VT, Chen W, Shi J, Zhang M, Yang H, Wang N, Yang S, Li J, Yang P, Fei J.
Exp Gerontol. 2019 Mar;117:99-105. doi: 10.1016/j.exger.2018.11.016. Epub 2018 Nov 23.

Ganoderma lucidum Ameliorates Non-Alcoholic Steatosis by Upregulating Energy Metabolizing Enzymes in the Liver.
Jung S, Son H, Hwang CE, Cho KM, Park SW, Kim HJ.
J Clin Med. 2018 Jun 15;7(6). pii: E152. doi: 10.3390/jcm7060152.

Effect of the taxonomic group of fungi and type of substrate on the antioxidant activity of a solid-state fermentation system.
El-Katony TM, El-Dein MMN, El-Fallal AA, Ibrahim NG.
Int Microbiol. 2018 Nov 9. doi: 10.1007/s10123-018-00040-6. 

Evaluation of the Antioxidative and Hypo-cholesterolemic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Ameliorating Cardiovascular Disease.
Rahman MA, Abdullah N, Aminudin N.
Int J Med Mushrooms. 2018;20(10):961-969. doi: 10.1615/IntJMedMushrooms.2018028370.

Bioprospecting of Wild Mushrooms from India with Respect to Their Medicinal Aspects.
Khan F, Chandra R.
Int J Med Mushrooms. 2019;21(2):181-192. doi: 10.1615/IntJMedMushrooms.2019029969.

Effects of Concurrently Administered Aqueous Extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), and Lead Acetate in Rats.
Sobowale MT, Ozolua RI, Uwaya DO, Ayinde BA.
Int J Med Mushrooms. 2019;21(2):143-154. doi: 10.1615/IntJMedMushrooms.2019029766.

Protective effects of Ganoderma triterpenoids on cadmium-induced oxidative stress and inflammatory injury in chicken livers.
Li T, Yu H, Song Y, Zhang R, Ge M.
J Trace Elem Med Biol. 2019 Mar;52:118-125. doi: 10.1016/j.jtemb.2018.12.010. Epub 2018 Dec 15.

Porous Yolk-Shell Particle Engineering via Nonsolvent-Assisted Trineedle Coaxial Electrospraying for Burn-Related Wound Healing.
Zhang C, Li Y, Hu Y, Peng Y, Ahmad Z, Li JS, Chang MW.
ACS Appl Mater Interfaces. 2019 Feb 27;11(8):7823-7835. doi: 10.1021/acsami.8b22112. Epub 2019 Feb 19.

De novo transcriptome assembly and protein profiling of copper-induced lignocellulolytic fungus Ganoderma lucidum MDU-7 reveals genes involved in lignocellulose degradation and terpenoid biosynthetic pathways.
Jain KK, Kumar A, Shankar A, Pandey D, Chaudhary B, Sharma KK.
Genomics. 2019 Jan 26. pii: S0888-7543(18)30526-3. doi: 10.1016/j.ygeno.2019.01.012.

Antioxidant and Anti-Inflammatory Activity and Cytotoxicity of Ethanol Extracts from Rhynchosia nulubilis Cultivated with Ganoderma lucidum Mycelium.
Park MH, Kim M.
Prev Nutr Food Sci. 2018 Dec;23(4):326-334. doi: 10.3746/pnf.2018.23.4.326. Epub 2018 Dec 31.

Phenolic Rich Fractions from Mycelium and Fruiting Body of Ganoderma lucidum Inhibit Bacterial Pathogens Mediated by Generation of Reactive Oxygen Species and Protein Leakage and Modulate Hypoxic Stress in HEK 293 Cell Line.
Mishra J, Joshi A, Rajput R, Singh K, Bansal A, Misra K.
Adv Pharmacol Sci. 2018 Dec 17;2018:6285615. doi: 10.1155/2018/6285615. eCollection 2018.

Effects of Fungal Polysaccharide on Oxidative Damage and TLR4 Pathway to the Central Immune Organs in Cadmium Intoxication in Chickens.
Li R, Zhang L, Tang Z, Li T, Li G, Zhang R, Ge M.
Biol Trace Elem Res. 2019 Jan 10. doi: 10.1007/s12011-018-1627-0. 

Effects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides.
Zeng X, Li P, Chen X, Kang Y, Xie Y, Li X, Xie T, Zhang Y.
Int J Biol Macromol. 2019 Apr 1;126:867-876. doi: 10.1016/j.ijbiomac.2018.12.222. Epub 2018 Dec 24.

Medium composition optimization, structural characterization, and antioxidant activity of exopolysaccharides from the medicinal mushroom Ganoderma lingzhi.
Si J, Meng G, Wu Y, Ma HF, Cui BK, Dai YC.
Int J Biol Macromol. 2019 Mar 1;124:1186-1196. doi: 10.1016/j.ijbiomac.2018.11.274. Epub 2018 Dec 3.

Phytochemical composition, antioxidant and antiproliferative activities and effects on nuclear DNA of ethanolic extract from an Italian mycelial isolate of Ganoderma lucidum.
Saltarelli R, Palma F, Gioacchini AM, Calcabrini C, Mancini U, De Bellis R, Stocchi V, Potenza L.
J Ethnopharmacol. 2019 Mar 1;231:464-473. doi: 10.1016/j.jep.2018.11.041. Epub 2018 Dec 1.

Antioxidant potential of ganoderic acid in Notch-1 protein in neuroblastoma.
Gill BS, Navgeet, Kumar S.
Mol Cell Biochem. 2018 Dec 3. doi: 10.1007/s11010-018-3485-7. 

Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction.
Kang Q, Chen S, Li S, Wang B, Liu X, Hao L, Lu J.
Int J Biol Macromol. 2019 Mar 1;124:1137-1144. doi: 10.1016/j.ijbiomac.2018.11.215. Epub 2018 Nov 24.

Ganoderma tsugae induced ROS-independent apoptosis and cytoprotective autophagy in human chronic myeloid leukemia cells.
Hseu YC, Shen YC, Kao MC, Mathew DC, Karuppaiya P, Li ML, Yang HL.
Food Chem Toxicol. 2019 Feb;124:30-44. doi: 10.1016/j.fct.2018.11.043. Epub 2018 Nov 19.

The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients.
Sargowo D, Ovianti N, Susilowati E, Ubaidillah N, Widya Nugraha A, Vitriyaturrida, Siwi Proboretno K, Failasufi M, Ramadhan F, Wulandari H, Waranugraha Y, Hayuning Putri D.
Indian Heart J. 2018 Sep - Oct;70(5):608-614. doi: 10.1016/j.ihj.2017.12.007. Epub 2017 Dec 14.

Ganoderma lucidum polysaccharide inhibits UVB-induced melanogenesis by antagonizing cAMP/PKA and ROS/MAPK signaling pathways.
Hu S, Huang J, Pei S, Ouyang Y, Ding Y, Jiang L, Lu J, Kang L, Huang L, Xiang H, Xiao R, Zeng Q, Chen J.
J Cell Physiol. 2019 May;234(5):7330-7340. doi: 10.1002/jcp.27492. Epub 2018 Oct 26.

Meroterpenoids from Ganoderma sinense protect hepatocytes and cardiomyocytes from oxidative stress induced injuries.
Gao S, Zhang P, Zhang C, Bao F, Li H, Chen L.
Fitoterapia. 2018 Nov;131:73-79. doi: 10.1016/j.fitote.2018.10.009. Epub 2018 Oct 9.

Hyperproduction of exopolysaccharides by submerged mycelial culture of Ganoderma lucidum using a solid seed grown in fine-powder of wheat bran and in vitro evaluation of the antioxidant activity of the exopolysaccharides produced.
Liu SR, Zhang WR.
Food Sci Biotechnol. 2018 Feb 28;27(4):1129-1136. doi: 10.1007/s10068-018-0343-z. eCollection 2018 Aug. Erratum in: Food Sci Biotechnol. 2018 Jun 12;27(4):1245. 

Targeting oxidative stress using tri-needle electrospray engineered Ganoderma lucidum polysaccharide-loaded porous yolk-shell particles.
Xing Z, Zhang C, Zhao C, Ahmad Z, Li JS, Chang MW.
Eur J Pharm Sci. 2018 Dec 1;125:64-73. doi: 10.1016/j.ejps.2018.09.016. Epub 2018 Sep 21.

Lanostane triterpenoids from Ganoderma luteomarginatum and their cytotoxicity against four human cancer cell lines.
Su HG, Zhou QM, Guo L, Huang YJ, Peng C, Xiong L.
Phytochemistry. 2018 Dec;156:89-95. doi: 10.1016/j.phytochem.2018.09.003. Epub 2018 Sep 18.

Hepatoprotective activity of Ganoderma lucidum triterpenoids in alcohol-induced liver injury in mice, an iTRAQ-based proteomic analysis.
Zhao C, Fan J, Liu Y, Guo W, Cao H, Xiao J, Wang Y, Liu B.
Food Chem. 2019 Jan 15;271:148-156. doi: 10.1016/j.foodchem.2018.07.115. Epub 2018 Jul 18.
Hypolipidemic, Antioxidant, and Antiapoptotic Effects of Polysaccharides Extracted from Reishi Mushroom, Ganoderma lucidum (Leysser: Fr) Karst, in Mice Fed a High-Fat Diet.
Liang Z, Yuan Z, Li G, Fu F, Shan Y.
J Med Food. 2018 Dec;21(12):1218-1227. doi: 10.1089/jmf.2018.4182. Epub 2018 Sep 5.
Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement.
Ahmad MF.
Biomed Pharmacother. 2018 Nov;107:507-519. doi: 10.1016/j.biopha.2018.08.036. Epub 2018 Aug 13. Review.

Phenolics, tocopherols and fatty acid profiling of wild and commercial mushrooms from Pakistan.
Sharif S, Rashid S, Atta A, Irshad A, Riaz M, Shahid M, Mustafa G.
J Biol Regul Homeost Agents. 2018 Jul-Aug;32(4):863-867.

Total Syntheses and Biological Evaluation of the Ganoderma lucidum Alkaloids Lucidimines B and C.
Chen Y, Lan P.
ACS Omega. 2018 Mar 31;3(3):3471-3481. doi: 10.1021/acsomega.8b00295. Epub 2018 Mar 26.

Hypolipidaemic and anti-lipidperoxidant activities of Ganoderma lucidum polysaccharide.
Wu S.
Int J Biol Macromol. 2018 Oct 15;118(Pt B):2001-2005. doi: 10.1016/j.ijbiomac.2018.07.082. Epub 2018 Jul 22.

Role of Mushroom as Dietary Supplement on Performance of Poultry.
Khan SH, Mukhtar N, Iqbal J.
J Diet Suppl. 2018 Jul 3:1-14. doi: 10.1080/19390211.2018.1472707.

Antioxidant and Hepatoprotective Activities of Crude Polysaccharide Extracts from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), by Ultrasonic-Circulating Extraction.
Chen TQ, Wu JG, Kan YJ, Yang C, Wu YB, Wu JZ.
Int J Med Mushrooms. 2018;20(6):581-593. doi: 10.1615/IntJMedMushrooms.2018026536.

Antioxidant Properties of the Artist's Conk Medicinal Mushroom, Ganoderma applanatum (Agaricomycetes), upon Cultivation with para-Substituted Phenolic Compounds and Tea Leaf Extracts.
Tsivileva O, Pankratov A, Misin V, Zavyalov A, Volkov V, Tsymbal O, Yurasov N, Nikitina VE.
Int J Med Mushrooms. 2018;20(6):549-560. doi: 10.1615/IntJMedMushrooms.2018026329.

Incorporation of tocopherol-rich extracts from mushroom mycelia into yogurt.
Bouzgarrou C, Amara K, Reis FS, Barreira JCM, Skhiri F, Chatti N, Martins A, Barros L, Ferreira ICFR.
Food Funct. 2018 Jun 20;9(6):3166-3172. doi: 10.1039/c8fo00482j.

Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats.
Hossen MS, Billah Prince MM, Tanvir EM, Chowdhury MAZ, Rahman MA, Alam F, Paul S, Saha M, Ali MY, Bhoumik NC, Karim N, Gan SH, Khalil MI.
Evid Based Complement Alternat Med. 2018 May 15;2018:6254929. doi: 10.1155/2018/6254929. eCollection 2018.

Ganoderma Triterpenoids Exert Antiatherogenic Effects in Mice by Alleviating Disturbed Flow-Induced Oxidative Stress and Inflammation.
Hsu PL, Lin YC, Ni H, Mo FE.
Oxid Med Cell Longev. 2018 Apr 11;2018:3491703. doi: 10.1155/2018/3491703. eCollection 2018.

Evaluation of diuron tolerance and biotransformation by the white-rot fungus Ganoderma lucidum.
Coelho-Moreira JDS, Brugnari T, Sá-Nakanishi AB, Castoldi R, de Souza CGM, Bracht A, Peralta RM.
Fungal Biol. 2018 Jun;122(6):471-478. doi: 10.1016/j.funbio.2017.10.008. Epub 2017 Nov 2.

Effect of Selenium-containing Biocomposites from Medicinal Mushrooms on the Potato Ring Rot Causative Agent.
Perfileva AI, Tsivileva OM, Drevko YB, Ibragimova DN, Koftin OV.
Dokl Biol Sci. 2018 Mar;479(1):67-69. doi: 10.1134/S0012496618020072. Epub 2018 May 22.

Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora.
Liu JQ, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, Liu ZQ, Qiu SQ, Cheng BH.
Food Chem. 2018 Oct 15;263:155-162. doi: 10.1016/j.foodchem.2018.04.097. Epub 2018 Apr 25.

Cell Proliferation and DNA Repair Ability of Ganoderma neo-japonicum (Agaricomycetes): An Indigenous Medicinal Mushroom from Malaysia.
Tan WC, Kuppusamy UR, Phan CW, Sabaratnam V.
Int J Med Mushrooms. 2018;20(2):155-163. doi: 10.1615/IntJMedMushrooms.2018025445.

Antimelanogenesis and Anti-Inflammatory Activity of Selected Culinary-Medicinal Mushrooms.
Saad HM, Sim KS, Tan YS.
Int J Med Mushrooms. 2018;20(2):141-153. doi: 10.1615/IntJMedMushrooms.2018025463.

Combinatorial usage of fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum ameliorate drug-induced liver injury in mice.
Fan S, Huang X, Wang S, Li C, Zhang Z, Xie M, Nie S.
Food Chem Toxicol. 2018 Sep;119:66-72. doi: 10.1016/j.fct.2018.05.027. Epub 2018 May 16.

In vitro evaluation of the synergistic antioxidant and anti-inflammatory activities of the combined extracts from Malaysian Ganoderma lucidum and Egyptian Chlorella vulgaris.
Abu-Serie MM, Habashy NH, Attia WE.
BMC Complement Altern Med. 2018 May 10;18(1):154. doi: 10.1186/s12906-018-2218-5.

Hypouricemic Effect of 2,5-Dihydroxyacetophenone, a Computational Screened Bioactive Compound from Ganoderma applanatum, on Hyperuricemic Mice.
Liang D, Yong T, Chen S, Xie Y, Chen D, Zhou X, Li D, Li M, Su L, Zuo D.
Int J Mol Sci. 2018 May 7;19(5). pii: E1394. doi: 10.3390/ijms19051394.

Antioxidant Enzyme Activities and Secondary Metabolite Profiling of Oil Palm Seedlings Treated with Combination of NPK Fertilizers Infected with Ganoderma boninense.
Sahebi M, Hanafi MM, Mohidin H, Rafii MY, Azizi P, Idris AS, Fariz A, Abiri R, Taheri S, Moradpoor M.
Biomed Res Int. 2018 Mar 12;2018:1494157. doi: 10.1155/2018/1494157. eCollection 2018.

Novel Kombucha Beverage from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum, with Antibacterial and Antioxidant Effects.
Sknepnek A, Pantić M, Matijašević D, Miletić D, Lević S, Nedović V, Niksic M.
Int J Med Mushrooms. 2018;20(3):243-258. doi: 10.1615/IntJMedMushrooms.2018025833.

Protective Effect of Ganoderma Triterpenoids on Cadmium-Induced Testicular Toxicity in Chickens.
Wang H, Zhang R, Song Y, Li T, Ge M.
Biol Trace Elem Res. 2019 Jan;187(1):281-290. doi: 10.1007/s12011-018-1364-4. Epub 2018 May 2.

Structural Elucidation and Biomimetic Synthesis of (±)-Cochlactone A with Anti-Inflammatory Activity.
Peng XR, Lu SY, Shao LD, Zhou L, Qiu MH.
J Org Chem. 2018 May 18;83(10):5516-5522. doi: 10.1021/acs.joc.8b00525. Epub 2018 May 4.

Chemical, biochemical, preclinical and clinical studies of Ganoderma lucidum polysaccharide as an approved drug for treating myopathy and other diseases in China.
Zeng P, Guo Z, Zeng X, Hao C, Zhang Y, Zhang M, Liu Y, Li H, Li J, Zhang L.
J Cell Mol Med. 2018 Jul;22(7):3278-3297. doi: 10.1111/jcmm.13613. Epub 2018 Apr 24. Review.

Development of antler-type fruiting bodies of Ganoderma lucidum and determination of its biochemical properties.
Sudheer S, Taha Z, Manickam S, Ali A, Cheng PG.
Fungal Biol. 2018 May;122(5):293-301. doi: 10.1016/j.funbio.2018.01.007. Epub 2018 Feb 8.

Ganoderma lucidum Polysaccharide Peptide Attenuates Skin Flap Ischemia-Reperfusion Injury in a Thioredoxin-Dependent Manner.
Ren H, Meng X, Yin J, Sun J, Huang Q, Yin Z.
Plast Reconstr Surg. 2018 Jul;142(1):23e-33e. doi: 10.1097/PRS.0000000000004503.

Preparation of Bioactive Polysaccharide Nanoparticles with Enhanced Radical Scavenging Activity and Antimicrobial Activity.
Qin Y, Xiong L, Li M, Liu J, Wu H, Qiu H, Mu H, Xu X, Sun Q.
J Agric Food Chem. 2018 May 2;66(17):4373-4383. doi: 10.1021/acs.jafc.8b00388. Epub 2018 Apr 18.

Heat stress-induced reactive oxygen species participate in the regulation of HSP expression, hyphal branching and ganoderic acid biosynthesis in Ganoderma lucidum.
Liu R, Zhang X, Ren A, Shi DK, Shi L, Zhu J, Yu HS, Zhao MW.
Microbiol Res. 2018 Apr;209:43-54. doi: 10.1016/j.micres.2018.02.006. Epub 2018 Feb 19.

Racemic meroterpenoids from Ganoderma cochlear.
Peng X, Wang X, Chen L, Yang H, Li L, Lu S, Zhou L, Qiu M.
Fitoterapia. 2018 Jun;127:286-292. doi: 10.1016/j.fitote.2018.03.005. Epub 2018 Mar 11.

Effect of Ganoderma lucidum Powder on Oxidative Stability, Microbial and Sensory Properties of Emulsion Type Sausage.
Ghobadi R, Mohammadi R, Chabavizade J, Sami M.
Adv Biomed Res. 2018 Feb 16;7:24. doi: 10.4103/2277-9175.225595. eCollection 2018.

Emerging Roles of <i>Ganoderma Lucidum</i> in Anti-Aging.
Wang J, Cao B, Zhao H, Feng J.
Aging Dis. 2017 Dec 1;8(6):691-707. doi: 10.14336/AD.2017.0410. eCollection 2017 Dec. Review.

Effects of Ganoderma Lucidum shell-broken spore on oxidative stress of the rabbit urinary bladder using an in vivo model of ischemia/reperfusion.
Levin RM, Xia L, Wei W, Schuler C, Leggett RE, Lin AD.
Mol Cell Biochem. 2017 Nov;435(1-2):25-35. doi: 10.1007/s11010-017-3053-6. Epub 2017 May 8.

Determination of the Biological Efficiency and Antioxidant Potential of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Cultivated Using Different Agro-Wastes in Malaysia.
Sudheer S, Alzorqi I, Ali A, Cheng PG, Siddiqui Y, Manickam S.
Int J Med Mushrooms. 2018;20(1):89-100. doi: 10.1615/IntJMedMushrooms.2017024588.

Silver Nanoparticles Synthesized Using Wild Mushroom Show Potential Antimicrobial Activities against Food Borne Pathogens.
Mohanta YK, Nayak D, Biswas K, Singdevsachan SK, Abd Allah EF, Hashem A, Alqarawi AA, Yadav D, Mohanta TK.
Molecules. 2018 Mar 14;23(3). pii: E655. doi: 10.3390/molecules23030655.

Antitumour, Antimicrobial, Antioxidant and Antiacetylcholinesterase Effect of Ganoderma Lucidum Terpenoids and Polysaccharides: A Review.
Cör D, Knez Ž, Knez Hrnčič M.
Molecules. 2018 Mar 13;23(3). pii: E649. doi: 10.3390/molecules23030649. Review.

Ganoderic acid A potentiates the antioxidant effect and protection of mitochondrial membranes and reduces the apoptosis rate in primary hippocampal neurons in magnesium free medium.
Jiang ZM, Qiu HB, Wang SQ, Guo J, Yang ZW, Zhou SB.
Pharmazie. 2018 Feb 1;73(2):87-91. doi: 10.1691/ph.2018.7108.

Protective effects of a Ganoderma atrum polysaccharide against acrylamide induced oxidative damage via a mitochondria mediated intrinsic apoptotic pathway in IEC-6 cells.
Jiang G, Zhang L, Wang H, Chen Q, Wu X, Yan X, Chen Y, Xie M.
Food Funct. 2018 Feb 21;9(2):1133-1143. doi: 10.1039/c7fo01619k.

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), as a Cardioprotectant in an Oxygen-Deficient Environment.
Kirar V, Nehra S, Mishra J, Rakhee R, Saraswat D, Misra K.
Int J Med Mushrooms. 2017;19(11):1009-1021. doi: 10.1615/IntJMedMushrooms.2017024584.

Analysis of Antioxidant and Anti-Inflammatory Activities of Solvent Fractions from <i>Rhynchosia nulubilis</i> Cultivated with <i>Ganoderma lucidum</i> Mycelium.
Park M, Kim M.
Prev Nutr Food Sci. 2017 Dec;22(4):365-371. doi: 10.3746/pnf.2017.22.4.365. Epub 2017 Dec 31.

Ganoderma Lucidum Protects Rat Brain Tissue Against Trauma-Induced Oxidative Stress.
Özevren H, İrtegün S, Deveci E, Aşır F, Pektanç G, Deveci Ş.
Korean J Neurotrauma. 2017 Oct;13(2):76-84. doi: 10.13004/kjnt.2017.13.2.76. Epub 2017 Oct 31.
Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Inhibits Candida Biofilms: A Metabolomic Approach.
Bhardwaj A, Gupta P, Kumar N, Mishra J, Kumar A, Rakhee R, Misra K.
Int J Med Mushrooms. 2017;19(8):685-696. doi: 10.1615/IntJMedMushrooms.2017021225.

The inhibitory effects of polysaccharide peptides (PsP) of <i>Ganoderma lucidum</i> against atherosclerosis in rats with dyslipidemia.
Wihastuti TA, Heriansyah T.
Heart Int. 2017 Apr 12;12(1):e1-e7. doi: 10.5301/heartint.5000234. eCollection 2017 Jan-Dec.

Culture broth of <i>Ganoderma lucidum</i> exhibited antioxidant, antibacterial and α-amylase inhibitory activities.
Sarnthima R, Khammaung S, Sa-Ard P.
J Food Sci Technol. 2017 Oct;54(11):3724-3730. doi: 10.1007/s13197-017-2839-6. Epub 2017 Sep 7.

Effect of heat stress on production and in-vitro antioxidant activity of polysaccharides in Ganoderma lucidum.
Tan X, Sun J, Xu Z, Li H, Hu J, Ning H, Qin Z, Pei H, Sun T, Zhang X.
Bioprocess Biosyst Eng. 2018 Jan;41(1):135-141. doi: 10.1007/s00449-017-1850-7. Epub 2017 Oct 10.

Retraction Notice: Liquid Fermentation of <i>Ganoderma applanatum</i> and Antioxidant Activity of Exopolysaccharides.
Zhong-Hua L, Xiao-Ge H, Jin-Hui Z, Le HE.
Open Biomed Eng J. 2016 Dec 30;10:114. doi: 10.2174/1874120701610010114. eCollection 2016.

Effects of Ganoderma lucidum polysaccharides against doxorubicin-induced cardiotoxicity.
Xu F, Li X, Xiao X, Liu LF, Zhang L, Lin PP, Zhang SL, Li QS.
Biomed Pharmacother. 2017 Nov;95:504-512. doi: 10.1016/j.biopha.2017.08.118. Epub 2017 Sep 12.

Ornithine Decarboxylase-Mediated Production of Putrescine Influences Ganoderic Acid Biosynthesis by Regulating Reactive Oxygen Species in Ganoderma lucidum.
Wu CG, Tian JL, Liu R, Cao PF, Zhang TJ, Ren A, Shi L, Zhao MW.
Appl Environ Microbiol. 2017 Sep 29;83(20). pii: e01289-17. doi: 10.1128/AEM.01289-17. Print 2017 Oct 15.

The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits.
Taofiq O, Heleno SA, Calhelha RC, Alves MJ, Barros L, González-Paramás AM, Barreiro MF, Ferreira ICFR.
Food Chem Toxicol. 2017 Oct;108(Pt A):139-147. doi: 10.1016/j.fct.2017.07.051. Epub 2017 Jul 29.

Wild Mushrooms: A Potential Source of Nutritional and Antioxidant Attributes with Acceptable Toxicity.
Sharif S, Shahid M, Mushtaq M, Akram S, Rashid A.
Prev Nutr Food Sci. 2017 Jun;22(2):124-130. doi: 10.3746/pnf.2017.22.2.124. Epub 2017 Jun 30.

Protective effect of Ganoderma lucidum polysaccharide against carbon tetrachloride-induced hepatic damage in precision-cut carp liver slices.
Liu Y, Zhang C, Du J, Jia R, Cao L, Jeney G, Teraoka H, Xu P, Yin G.
Fish Physiol Biochem. 2017 Oct;43(5):1209-1221. doi: 10.1007/s10695-016-0333-0. Epub 2017 Jul 5.

Anti-amnesic effects of Ganoderma species: A possible cholinergic and antioxidant mechanism.
Kaur R, Singh V, Shri R.
Biomed Pharmacother. 2017 Aug;92:1055-1061. doi: 10.1016/j.biopha.2017.06.029. Epub 2017 Jun 10.

Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth.
Dogan MS, Yavas MC, Yavuz Y, Erdogan S, Yener İ, Simsek İ, Akkus Z, Eratilla V, Tanik A, Akdag MZ.
Drug Des Devel Ther. 2017 May 4;11:1393-1398. doi: 10.2147/DDDT.S132308. eCollection 2017.

Chemical composition, antiproliferative and antioxidant activity of differently processed <i>Ganoderma lucidum</i> ethanol extracts.
Veljović S, Veljović M, Nikićević N, Despotović S, Radulović S, Nikšić M, Filipović L.
J Food Sci Technol. 2017 Apr;54(5):1312-1320. doi: 10.1007/s13197-017-2559-y. Epub 2017 Mar 10.

Structure and bioactivities of a polysaccharide isolated from Ganoderma lucidum in submerged fermentation.
Ai-Lati A, Liu S, Ji Z, Zhang H, Mao J.
Bioengineered. 2017 Sep 3;8(5):565-571. doi: 10.1080/21655979.2017.1283459. Epub 2017 Jan 31.
Ganoderma lucidum polysaccharides protect fibroblasts against UVB-induced photoaging.
Zeng Q, Zhou F, Lei L, Chen J, Lu J, Zhou J, Cao K, Gao L, Xia F, Ding S, Huang L, Xiang H, Wang J, Xiao Y, Xiao R, Huang J.
Mol Med Rep. 2017 Jan;15(1):111-116. doi: 10.3892/mmr.2016.6026. Epub 2016 Dec 12.

Ganoderma atrum polysaccharide ameliorates ROS generation and apoptosis in spleen and thymus of immunosuppressed mice.
Li WJ, Li L, Zhen WY, Wang LF, Pan M, Lv JQ, Wang F, Yao YF, Nie SP, Xie MY.
Food Chem Toxicol. 2017 Jan;99:199-208. doi: 10.1016/j.fct.2016.11.033. Epub 2016 Nov 30.

Ethanol Extract of Ganoderma lucidum Augments Cellular Anti-oxidant Defense through Activation of Nrf2/HO-1.
Lee YH, Kim JH, Song CH, Jang KJ, Kim CH, Kang JS, Choi YH, Yoon HM.
J Pharmacopuncture. 2016 Mar;19(1):59-69. doi: 10.3831/KPI.2016.19.008.

Purification, structural characterization and in vitro antioxidant activity of a novel polysaccharide from Boshuzhi.
Jiang J, Kong F, Li N, Zhang D, Yan C, Lv H.
Carbohydr Polym. 2016 Aug 20;147:365-71. doi: 10.1016/j.carbpol.2016.04.001. Epub 2016 Apr 2.

Chemical Characterization and Antioxidant Potential of Wild Ganoderma Species from Ghana.
Obodai M, Mensah DL, Fernandes Â, Kortei NK, Dzomeku M, Teegarden M, Schwartz SJ, Barros L, Prempeh J, Takli RK, Ferreira IC.
Molecules. 2017 Jan 25;22(2). pii: E196. doi: 10.3390/molecules22020196.

Ganoderma atrum polysaccharide ameliorates anoxia/reoxygenation-mediated oxidative stress and apoptosis in human umbilical vein endothelial cells.
Zhang YS, Li WJ, Zhang XY, Yan YX, Nie SP, Gong DM, Tang XF, He M, Xie MY.
Int J Biol Macromol. 2017 May;98:398-406. doi: 10.1016/j.ijbiomac.2017.01.071. Epub 2017 Jan 17.

Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps.
Cilerdzic J, Stajic M, Zivkovic L, Vukojevic J, Bajic V, Spremo-Potparevic B.
Int J Med Mushrooms. 2016;18(12):1061-1069. doi: 10.1615/IntJMedMushrooms.v18.i12.10.

Effects of Ganoderma lucidum polysaccharides on chronic pancreatitis and intestinal microbiota in mice.
Li K, Zhuo C, Teng C, Yu S, Wang X, Hu Y, Ren G, Yu M, Qu J.
Int J Biol Macromol. 2016 Dec;93(Pt A):904-912. doi: 10.1016/j.ijbiomac.2016.09.029. Epub 2016 Sep 9.

Effect of Oral Coadministration of Ascorbic Acid with Ling Zhi Preparation on Pharmacokinetics of Ganoderic Acid A in Healthy Male Subjects: A Randomized Crossover Study.
Tawasri P, Ampasavate C, Tharatha S, Chiranthanut N, Teekachunhatean S.
Biomed Res Int. 2016;2016:2819862. Epub 2016 Sep 25.

Involvement of metabolites in early defense mechanism of oil palm (Elaeis guineensis Jacq.) against Ganoderma disease.
Nusaibah SA, Siti Nor Akmar A, Idris AS, Sariah M, Mohamad Pauzi Z.
Plant Physiol Biochem. 2016 Dec;109:156-165. doi: 10.1016/j.plaphy.2016.09.014. Epub 2016 Sep 19.

Comparison of the Chemical Profiles and Antioxidant and Antidiabetic Activities of Extracts from Two Ganoderma Species (Agaricomycetes).
Tang X, Cai W, Xu B.
Int J Med Mushrooms. 2016;18(7):609-20.

Species of Genus Ganoderma (Agaricomycetes) Fermentation Broth: A Novel Antioxidant and Antimicrobial Agent.
Cilerdzic J, Kosanic M, Stajić M, Vukojevic J, Ranković B.
Int J Med Mushrooms. 2016;18(5):397-404.

Transubstantiating commercial mushroom market with ultrasonically ultrasized mushroom powders showcasing higher bioactivity.
Shang X, Enkhtaivan G, Chun S, Gopal J, Keum YS.
Int J Biol Macromol. 2016 Nov;92:1082-1094. doi: 10.1016/j.ijbiomac.2016.07.103. Epub 2016 Aug 5.

Diversity of Polypore Bracket Mushrooms, Polyporales (Agaricomycetes), Recorded in Armenia and Their Medicinal Properties.
Badalyan SM, Gharibyan NG.
Int J Med Mushrooms. 2016;18(4):347-54. doi: 10.1615/IntJMedMushrooms.v18.i4.80.

Protective roles of polysaccharides from Ganoderma lucidum on bleomycin-induced pulmonary fibrosis in rats.
Chen J, Shi Y, He L, Hao H, Wang B, Zheng Y, Hu C.
Int J Biol Macromol. 2016 Nov;92:278-281. doi: 10.1016/j.ijbiomac.2016.07.005. Epub 2016 Jul 2.

Ganoderma Lucidum polysaccharides protect against MPP(+) and rotenone-induced apoptosis in primary dopaminergic cell cultures through inhibiting oxidative stress.
Guo SS, Cui XL, Rausch WD.
Am J Neurodegener Dis. 2016 Jun 1;5(2):131-44. eCollection 2016 Jun 1.

Screening of Indian Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes): A UPC2-SQD-MS Approach.
Bhardwaj A, Srivastava M, Pal M, Sharma YK, Bhattacharya S, Tulsawani R, Sugadev R, Misra K.
Int J Med Mushrooms. 2016;18(2):177-89. doi: 10.1615/IntJMedMushrooms.v18.i2.80.
Ultrasonically extracted β-d-glucan from artificially cultivated mushroom, characteristic properties and antioxidant activity.
Alzorqi I, Sudheer S, Lu TJ, Manickam S.
Ultrason Sonochem. 2017 Mar;35(Pt B):531-540. doi: 10.1016/j.ultsonch.2016.04.017. Epub 2016 Apr 26.

Antioxidant farnesylated hydroquinones from Ganoderma capense.
Peng X, Li L, Wang X, Zhu G, Li Z, Qiu M.
Fitoterapia. 2016 Jun;111:18-23. doi: 10.1016/j.fitote.2016.04.006. Epub 2016 Apr 13.

Optimization of ultrasound induced emulsification on the formulation of palm-olein based nanoemulsions for the incorporation of antioxidant β-D-glucan polysaccharides.
Alzorqi I, Ketabchi MR, Sudheer S, Manickam S.
Ultrason Sonochem. 2016 Jul;31:71-84. doi: 10.1016/j.ultsonch.2015.12.004. Epub 2015 Dec 8.

Antioxidant and anticholinesterase activities of five wild mushroom species with total bioactive contents.
Tel G, Ozturk M, Duru ME, Turkoglu A.
Pharm Biol. 2015 Feb 27:1-7. [Epub ahead of print]

Biochemical characterization and antioxidant and antiproliferative activities of different ganoderma collections.
Saltarelli R, Ceccaroli P, Buffalini M, Vallorani L, Casadei L, Zambonelli A, Iotti M, Badalyan S, Stocchi V.
J Mol Microbiol Biotechnol. 2015;25(1):16-25. doi: 10.1159/000369212. Epub 2015 Feb 3.

Structural characterization and antioxidant activity of a heteropolysaccharide from Ganoderma capense.
Yi P, Li N, Wan JB, Zhang D, Li M, Yan C.
Carbohydr Polym. 2015 May 5;121:183-9. doi: 10.1016/j.carbpol.2014.11.034. Epub 2014 Nov 24.

Anti-inflammatory and hepatoprotective effects of Ganoderma lucidum polysaccharides on carbon tetrachloride-induced hepatocyte damage in common carp (Cyprinus carpio L.).
Liu YJ, Du JL, Cao LP, Jia R, Shen YJ, Zhao CY, Xu P, Yin GJ.
Int Immunopharmacol. 2015 Mar;25(1):112-20. doi: 10.1016/j.intimp.2015.01.023. Epub 2015 Jan 29.

Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities.
Ferreira IC, Heleno SA, Reis FS, Stojkovic D, Queiroz MJ, Vasconcelos MH, Sokovic M.
Phytochemistry. 2014 Nov 5. pii: S0031-9422(14)00415-4. doi: 10.1016/j.phytochem.2014.10.011. [Epub ahead of print] Review.

A comprehensive review of the structure elucidation and biological activity of triterpenoids from Ganoderma spp.
Xia Q, Zhang H, Sun X, Zhao H, Wu L, Zhu D, Yang G, Shao Y, Zhang X, Mao X, Zhang L, She G.
Molecules. 2014 Oct 30;19(11):17478-535. doi: 10.3390/molecules191117478.

Fungal beta glucan protects radiation induced DNA damage in human lymphocytes.
Pillai TG, Maurya DK, Salvi VP, Janardhanan KK, Nair CK.
Ann Transl Med. 2014 Feb;2(2):13. doi: 10.3978/j.issn.2305-5839.2014.02.02.

Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear.
Peng X, Liu J, Wang C, Han Z, Shu Y, Li X, Zhou L, Qiu M.
Food Chem. 2015 Mar 15;171:251-7. doi: 10.1016/j.foodchem.2014.08.127. Epub 2014 Sep 8.

The level of elements and antioxidant activity of commercial dietary supplement formulations based on edible mushrooms.
Stilinović N, Škrbić B, Živančev J, Mrmoš N, Pavlović N, Vukmirović S.
Food Funct. 2014 Dec;5(12):3170-8. doi: 10.1039/c4fo00703d.

Modulatory effect of crude aqueous extract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Higher Basidiomycetes), on hematological and antioxidant indices in Plasmodium berghei-infected mice.
Oluba OM, Adebisi KE, Eidangbe GO, Odutuga AA, Onyeneke EC.
Int J Med Mushrooms. 2014;16(5):499-506.

Development of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (Higher Basidiomycetes) polysaccharides injection formulation.
Jiang Y, He A, Liu Y, Xie B, Li Y, Deng Y, Liu X, Liu Q.
Int J Med Mushrooms. 2014;16(5):411-9.

Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.
Choi S, Nguyen VT, Tae N, Lee S, Ryoo S, Min BS, Lee JH.
Toxicol Appl Pharmacol. 2014 Nov 1;280(3):434-42. doi: 10.1016/j.taap.2014.09.007. Epub 2014 Sep 16.

Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology.
Kan Y, Chen T, Wu Y, Wu J, Wu J.
Int J Biol Macromol. 2015 Jan;72:151-7. doi: 10.1016/j.ijbiomac.2014.07.056. Epub 2014 Aug 19.

Optimization of laccase production by two strains of Ganoderma lucidum using phenolic and metallic inducers.
Kuhar F, Papinutti L.
Rev Argent Microbiol. 2014 Apr-Jun;46(2):144-9. doi: 10.1016/S0325-7541(14)70063-X.

Inflammatory modulation effect of glycopeptide from Ganoderma capense (Lloyd) Teng.
Zhou Y, Chen S, Ding R, Yao W, Gao X.
Mediators Inflamm. 2014;2014:691285. doi: 10.1155/2014/691285. Epub 2014 May 22.

Solid-substrate fermentation of wheat grains by mycelia of indigenous species of the genus Ganoderma (higher Basidiomycetes) to enhance the antioxidant activities.
Subramaniam S, Sabaratnam V, Kuppusamy UR, Tan YS.
Int J Med Mushrooms. 2014;16(3):259-67.

Biological activity of Ganoderma lucidum basidiocarps cultivated on alternative and commercial substrate.
Cilerdžić J, Vukojević J, Stajić M, Stanojković T, Glamočlija J.
J Ethnopharmacol. 2014 Aug 8;155(1):312-9. doi: 10.1016/j.jep.2014.05.036. Epub 2014 May 29.

Improving Training Condition Assessment in Endurance Cyclists: Effects of Ganoderma lucidum and Ophiocordyceps sinensis Dietary Supplementation.
Rossi P, Buonocore D, Altobelli E, Brandalise F, Cesaroni V, Iozzi D, Savino E, Marzatico F.
Evid Based Complement Alternat Med. 2014;2014:979613. doi: 10.1155/2014/979613. Epub 2014 Apr 1.

Improved production, purification and bioactivity of a polysaccharide from submerged cultured Ganoderma lucidum.
Zhou H, Liu G, Huang F, Wu X, Yang H.
Arch Pharm Res. 2014 Dec;37(12):1530-7. doi: 10.1007/s12272-014-0391-8. Epub 2014 Apr 16.

Wild Mushrooms in Nepal: Some Potential Candidates as Antioxidant and ACE-Inhibition Sources.
Hai Bang T, Suhara H, Doi K, Ishikawa H, Fukami K, Parajuli GP, Katakura Y, Yamashita S, Watanabe K, Adhikari MK, Manandhar HK, Kondo R, Shimizu K.
Evid Based Complement Alternat Med. 2014;2014:195305. doi: 10.1155/2014/195305. Epub 2014 Jan 28.

Effects of Selenium-Enriched Protein from Ganoderma lucidum on the Levels of IL-1 β and TNF- α , Oxidative Stress, and NF- κ B Activation in Ovalbumin-Induced Asthmatic Mice.
Min-Chang G, Wei-Hong T, Zhen X, Jie S.
Evid Based Complement Alternat Med. 2014;2014:182817. doi: 10.1155/2014/182817. Epub 2014 Feb 10.

Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
Phan CW, David P, Naidu M, Wong KH, Sabaratnam V.
Crit Rev Biotechnol. 2014 Mar 24. [Epub ahead of print]

Acetylation and carboxymethylation of the polysaccharide from Ganoderma atrum and their antioxidant and immunomodulating activities.
Chen Y, Zhang H, Wang Y, Nie S, Li C, Xie M.
Food Chem. 2014 Aug 1;156:279-88. doi: 10.1016/j.foodchem.2014.01.111. Epub 2014 Feb 7.

Immunomodulatory of selenium nano-particles decorated by sulfated Ganoderma lucidum polysaccharides.
Wang J, Zhang Y, Yuan Y, Yue T.
Food Chem Toxicol. 2014 Jun;68:183-9. doi: 10.1016/j.fct.2014.03.003. Epub 2014 Mar 10.

Ganoderma lucidum polysaccharides supplementation attenuates exercise-induced oxidative stress in skeletal muscle of mice.
Zhonghui Z, Xiaowei Z, Fang F.
Saudi J Biol Sci. 2014 Apr;21(2):119-23. doi: 10.1016/j.sjbs.2013.04.004. Epub 2013 Apr 23.

Effect of ultrasonic extraction conditions on antioxidative and immunomodulatory activities of a Ganoderma lucidum polysaccharide originated from fermented soybean curd residue.
Shi M, Yang Y, Hu X, Zhang Z.
Food Chem. 2014 Jul 15;155:50-6. doi: 10.1016/j.foodchem.2014.01.037. Epub 2014 Jan 23.

Immunostimulatory activities of β-d-glucan from Ganoderma Lucidum.
Wang J, Yuan Y, Yue T.
Carbohydr Polym. 2014 Feb 15;102:47-54. doi: 10.1016/j.carbpol.2013.10.087. Epub 2013 Nov 6.

Ganodermasides C and D, two new anti-aging ergosterols from spores of the medicinal mushroom Ganoderma lucidum.
Weng Y, Lu J, Xiang L, Matsuura A, Zhang Y, Huang Q, Qi J.
Biosci Biotechnol Biochem. 2011;75(4):800-3.

[Effect of different light of LED light quality on growth and antioxidant enzyme activities of Ganoderma lucidum].
Wang L, Chen X, Wang Q, Hao J, Lan J.
Zhongguo Zhong Yao Za Zhi. 2011 Sep;36(18):2471-4. Chinese.

Antimicrobial properties, antioxidant activity and cytotoxicity of ethanol-soluble acidic components from Ganoderma atrum.
Li WJ, Nie SP, Liu XZ, Zhang H, Yang Y, Yu Q, Xie MY.
Food Chem Toxicol. 2011 Dec 16;50(3-4):689-694.

Structural characterization and antioxidative activity of low-molecular-weights beta-1,3-glucan from the residue of extracted Ganoderma lucidum fruiting bodies.
Kao PF, Wang SH, Hung WT, Liao YH, Lin CM, Yang WB.
J Biomed Biotechnol. 2012;2012:673764. Epub 2011 Dec 6.

Determination of the antioxidant activity and polyphenol contents of wild Lingzhi or reishi medicinal mushroom, ganoderma lucidum (W.Curt. Fr.) P. Karst. (higher basidiomycetes) from central himalayan hills of India.
Mohsin M, Negi P, Ahmed Z.
Int J Med Mushrooms. 2011;13(6):535-44.

Antioxidant activities of Ganoderma lucidum polysaccharides and their role on DNA damage in mice induced by cobalt-60 gamma-irradiation.
Zhao W, Jiang X, Deng W, Lai Y, Wu M, Zhang Z.
Food Chem Toxicol. 2012 Feb;50(2):303-9. Epub 2011 Nov 4.

Antioxidant activity and toxicity profile of total triterpenes isolated from Ganoderma lucidum (Fr.) P. Karst occurring in South India.
Smina TP, Mathew J, Janardhanan KK, Devasagayam TP.
Environ Toxicol Pharmacol. 2011 Nov;32(3):438-46. Epub 2011 Aug 30.

Environ Toxicol Pharmacol. 2011 Nov;32(3):438-46. Epub 2011 Aug 30.
Smina TP, De S, Devasagayam TP, Adhikari S, Janardhanan KK.
Mutat Res. 2011 Dec 24;726(2):188-94. Epub 2011 Sep 16.

Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3.
Hsieh TC, Wu JM.
Int J Mol Med. 2011 Dec;28(6):1065-9. doi: 10.3892/ijmm.2011.788.

Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes.
Sudheesh NP, Ajith TA, Janardhanan KK.
Int J Cardiol. 2011 Aug 22.

Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial.
Chu TT, Benzie IF, Lam CW, Fok BS, Lee KK, Tomlinson B.
Br J Nutr. 2011 Aug 1:1-11.

Ganoderma applanatum terpenes protect mouse liver against benzo(α)pyren-induced oxidative stress and inflammation.
Ma JQ, Liu CM, Qin ZH, Jiang JH, Sun YZ.
Environ Toxicol Pharmacol. 2011 May;31(3):460-8.

Polysaccharides purified from the submerged culture of Ganoderma formosanum stimulate macrophage activation and protect mice against Listeria monocytogenes infection.
Wang CL, Pi CC, Kuo CW, Zhuang YJ, Khoo KH, Liu WH, Chen CJ.
Biotechnol Lett. 2011 Nov;33(11):2271-8.

Evaluation of Selected Culinary-Medicinal Mushrooms for Antioxidant and ACE Inhibitory Activities.
Abdullah N, Ismail SM, Aminudin N, Shuib AS, Lau BF.
Evid Based Complement Alternat Med. 2012;2012:464238.

Effects of Ganoderma lucidum on obstructive jaundice-induced oxidative stress.
Aydin S, Aytac E, Uzun H, Altug T, Mansur B, Saygili S, Buyukpinarbasili N, Sariyar M.
Asian J Surg. 2010 Oct;33(4):173-80.

p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells.
Chen NH, Zhong JJ.
Phytomedicine. 2011 Jun 15;18(8-9):719-25. Epub 2011 Feb 25.

[Transformation of astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus]
Ruan M, Zhang LY, Yu B, Chen YS, Zhuang Y.
Zhong Yao Cai. 2010 Mar;33(3):339-43.            

In vitro effects of plant and mushroom extracts on immunological function of chicken lymphocytes and macrophages.
Lee SH, Lillehoj HS, Hong YH, Jang SI, Lillehoj EP, Ionescu C, Mazuranok L, Bravo D.
Br Poult Sci. 2010 Apr;51(2):213-21.     

[Effect of Ganoderma lucidum polysaccharides on hemodynamic and antioxidation in T2DM rats]
Xue H, Qiao J, Meng G, Wu F, Luo J, Chen H, Zheng H, Xu J.
Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(3):339-43.            

Ganoderma atrum polysaccharide protects cardiomyocytes against anoxia/reoxygenation-induced oxidative stress by mitochondrial pathway.
Li WJ, Nie SP, Chen Y, Xie MY, He M, Yu Q, Yan Y.
J Cell Biochem. 2010 May;110(1):191-200.     

Effects of sulfation on the physicochemical and functional properties of a water-insoluble polysaccharide preparation from Ganoderma lucidum.
Liu W, Wang H, Yao W, Gao X, Yu LL.
J Agric Food Chem. 2010 Mar 24;58(6):3336-41.     

Characterization and antioxidant activity of two low-molecular-weight polysaccharides purified from the fruiting bodies of Ganoderma lucidum.
Liu W, Wang H, Pang X, Yao W, Gao X.
Int J Biol Macromol. 2010 May 1;46(4):451-7.  

Medicinal mushroom Ganoderma lucidum (Leyss: Fr) Karst. triggers immunomodulatory effects and reduces nitric oxide synthesis in mice.
Rubel R, Dalla Santa HS, Bonatto SJ, Bello S, Fernandes LC, Di Bernardi R, Gern J, Santos CA, Soccol CR.
J Med Food. 2010 Feb;13(1):142-8.     

Therapeutic potential of Ganoderma lucidum (Fr.) P. Karst. against the declined antioxidant status in the mitochondria of post-mitotic tissues of aged mice.
Sudheesh NP, Ajith TA, Ramnath V, Janardhanan KK.
Clin Nutr. 2010 Jun;29(3):406-12.

Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern Parts of India.
Pillai TG, John M, Sara Thomas G.
Exp Toxicol Pathol. 2009 Dec 2.

HPLC analysis of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes activity and Bax, Bcl-2 expression.
Yang Q, Wang S, Xie Y, Sun J, Wang J.
Int J Biol Macromol. 2010 Mar 1;46(2):167-72.   

Effects of mushroom-derived beta-glucan-rich polysaccharide extracts on nitric oxide production by bone marrow-derived macrophages and nuclear factor-kappaB transactivation in Caco-2 reporter cells: can effects be explained by structure?
Volman JJ, Helsper JP, Wei S, Baars JJ, van Griensven LJ, Sonnenberg AS, Mensink RP, Plat J.
Mol Nutr Food Res. 2010 Feb;54(2):268-76.

Ganodermasides A and B, two novel anti-aging ergosterols from spores of a medicinal mushroom Ganoderma lucidum on yeast via UTH1 gene.
Weng Y, Xiang L, Matsuura A, Zhang Y, Huang Q, Qi J.
Bioorg Med Chem. 2010 Feb;18(3):999-1002.

[Determination of the eliminating ratio of TCM polysaccharide to hydroxyl radical by kinetic fluorescent spectrophotometry]
Feng HP, Mo YY, Huang MS, Pan YQ, Fan HJ.
Zhong Yao Cai. 2009 Jul;32(7):1087-90.             : 19873737 [PubMed - indexed for MEDLINE]Related citations

Anticancer properties of Ganoderma lucidum methanol extracts in vitro and in vivo.
Harhaji Trajković LM, Mijatović SA, Maksimović-Ivanić DD, Stojanović ID, Momcilović MB, Tufegdzić SJ, Maksimović VM, Marjanović ZS, Stosić-Grujicić SD.
Nutr Cancer. 2009;61(5):696-707.

The protective effect of Ganoderma atrum polysaccharide against anoxia/reoxygenation injury in neonatal rat cardiomyocytes.
Li WJ, Nie SP, Yan Y, Zhu SB, Xie MY.
Life Sci. 2009 Oct 21;85(17-18):634-41.

Preparation, characterization, and antiproliferative activities of the Se-containing polysaccharide SeGLP-2B-1 from Se-enriched Ganoderma lucidum.
Shang D, Zhang J, Wen L, Li Y, Cui Q.
J Agric Food Chem. 2009 Sep 9;57(17):7737-42.

Isolating a cytoprotective compound from Ganoderma tsugae: effects on induction of Nrf-2-related genes in endothelial cells.
Wei YS, Wung BS, Lin YC, Hsieh CW.
Biosci Biotechnol Biochem. 2009 Aug;73(8):1757-63.

Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense.
Sato N, Ma CM, Komatsu K, Hattori M.
J Nat Prod. 2009 May 22;72(5):958-61.

Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat.
Sudheesh NP, Ajith TA, Janardhanan KK.
Biogerontology. 2009 Oct;10(5):627-36.

Free-radical scavenging and mitochondrial antioxidant activities of Reishi-Ganoderma lucidum (Curt: Fr) P. Karst and Arogyapacha-Trichopus zeylanicus Gaertn extracts.
Cherian E, Sudheesh NP, Janardhanan KK, Patani G.
J Basic Clin Physiol Pharmacol. 2009;20(4):289-307.

Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice.
Seto SW, Lam TY, Tam HL, Au AL, Chan SW, Wu JH, Yu PH, Leung GP, Ngai SM, Yeung JH, Leung PS, Lee SM, Kwan YW.
Phytomedicine. 2009 May;16(5):426-36.

Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats.
Ajith TA, Sudheesh NP, Roshny D, Abishek G, Janardhanan KK.
Exp Gerontol. 2009 Mar;44(3):219-23.

A new class of natural glycopeptides with sugar moiety-dependent antioxidant activities derived from Ganoderma lucidum fruiting bodies.
Wu Y, Wang D.
J Proteome Res. 2009 Feb;8(2):436-42.

Ganoderma lucidum: a potent pharmacological macrofungus.
Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS.
Curr Pharm Biotechnol. 2009 Dec;10(8):717-42.

Synergistic effect of laccase mediators on pentachlorophenol removal by Ganoderma lucidum laccase.
Jeon JR, Murugesan K, Kim YM, Kim EJ, Chang YS.
Appl Microbiol Biotechnol. 2008 Dec;81(4):783-90.

[Effects of cadmium stress on the antioxidative system in Ganoderma lucidum mycelia]
Wang SH, Zhang H, Cui YR, He QY, Zhang Q.
Ying Yong Sheng Tai Xue Bao. 2008 Jun;19(6):1355-61.

Selenium in edible mushrooms.
Falandysz J.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2008 Jul-Sep;26(3):256-99.

Supplementation of methionine enhanced the ergothioneine accumulation in the Ganoderma neo-japonicum mycelia.
Lee WY, Park EJ, Ahn JK.
Appl Biochem Biotechnol. 2009 Jul;158(1):213-21.

Phenolic compound concentration and antioxidant activities of edible and medicinal mushrooms from Korea.
Kim MY, Seguin P, Ahn JK, Kim JJ, Chun SC, Kim EH, Seo SH, Kang EY, Kim SL, Park YJ, Ro HM, Chung IM.
J Agric Food Chem. 2008 Aug 27;56(16):7265-70.

The dual roles of Ganoderma antioxidants on urothelial cell DNA under carcinogenic attack.
Yuen JW, Gohel MD.
J Ethnopharmacol. 2008 Jul 23;118(2):324-30.  

Hepatoprotective effects of Ganoderma lucidum peptides against D-galactosamine-induced liver injury in mice.
Shi Y, Sun J, He H, Guo H, Zhang S.
J Ethnopharmacol. 2008 May 22;117(3):415-9.

Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae.
Liao CH, Hsiao YM, Lin CH, Yeh CS, Wang JC, Ni CH, Hsu CP, Ko JL.
Food Chem Toxicol. 2008 May;46(5):1851-9.

Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum.
Lai CS, Yu MS, Yuen WH, So KF, Zee SY, Chang RC.
Brain Res. 2008 Jan 23;1190:215-24.

Indian medicinal mushrooms as a source of antioxidant and antitumor agents.
A Ajith T, K Janardhanan K.
J Clin Biochem Nutr. 2007 May;40(3):157-62. 

Molecular cloning and expression of a laccase from Ganoderma lucidum, and its antioxidative properties.
Joo SS, Ryu IW, Park JK, Yoo YM, Lee DH, Hwang KW, Choi HT, Lim CJ, Lee do I, Kim K.
Mol Cells. 2008 Feb 29;25(1):112-8.

Effect of Ganoderma lucidum on cytokine release by peritoneal macrophages.
Ahmadi K, Riazipour M.
Iran J Immunol. 2007 Dec;4(4):220-6.

Biodegradation of endocrine-disrupting bisphenol A by white rot fungus Irpex lacteus.
Shin EH, Choi HT, Song HG.
J Microbiol Biotechnol. 2007 Jul;17(7):1147-51. 

Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.
Li EK, Tam LS, Wong CK, Li WC, Lam CW, Wachtel-Galor S, Benzie IF, Bao YX, Leung PC, Tomlinson B.
Arthritis Rheum. 2007 Oct 15;57(7):1143-50. 

Biological properties of different protein extracts from selenium-enriched Ganoderma lucidum.
Du M, Wang C, Hu XS, Zhao GH.
Int J Food Sci Nutr. 2008 Mar;59(2):134-47. 

Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats.
Wang X, Zhao X, Li D, Lou YQ, Lin ZB, Zhang GL.
Biol Pharm Bull. 2007 Sep;30(9):1702-6. 

Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease.
Chen LW, Wang YQ, Wei LC, Shi M, Chan YS.
CNS Neurol Disord Drug Targets. 2007 Aug;6(4):273-81.

Antioxidant small phenolic ingredients in Inonotus obliquus (persoon) Pilat (Chaga).
Nakajima Y, Sato Y, Konishi T.
Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1222-6.

Immunomodulation of RAW264.7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum.
Ji Z, Tang Q, Zhang J, Yang Y, Jia W, Pan Y.
J Ethnopharmacol. 2007 Jul 25;112(3):445-50.

Enhancement of ATP generation capacity, antioxidant activity and immunomodulatory activities by Chinese Yang and Yin tonifying herbs.
Ko KM, Leung HY.
Chin Med. 2007 Mar 27;2:3.     

Salidroside production by hairy roots of Rhodiola sachalinensis obtained after transformation with Agrobacterium rhizogenes.
Zhou X, Wu Y, Wang X, Liu B, Xu H.
Biol Pharm Bull. 2007 Mar;30(3):439-42. 

Effect of polysaccharides from Ganoderma lucidum on streptozotocin-induced diabetic nephropathy in mice.
He CY, Li WD, Guo SX, Lin SQ, Lin ZB.
J Asian Nat Prod Res. 2006 Dec;8(8):705-11. 

[The pharmacological study of Ganoderma spores and their active components]
Lin ZB, Wang PY.
Beijing Da Xue Xue Bao. 2006 Oct 18;38(5):541-7.

Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion.
Thyagarajan A, Jiang J, Hopf A, Adamec J, Sliva D.
Int J Mol Med. 2006 Oct;18(4):657-64. 

Antimutagenic activity of methanolic extract of Ganoderma lucidum and its effect on hepatic damage caused by benzo[a]pyrene.
Lakshmi B, Ajith TA, Jose N, Janardhanan KK.
J Ethnopharmacol. 2006 Sep 19;107(2):297-303.

Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells.
Xie JT, Wang CZ, Wicks S, Yin JJ, Kong J, Li J, Li YC, Yuan CS.
Exp Oncol. 2006 Mar;28(1):25-9. 

In vitro and in vivo protective effects of proteoglycan isolated from mycelia of Ganoderma lucidum on carbon tetrachloride-induced liver injury.
Yang XJ, Liu J, Ye LB, Yang F, Ye L, Gao JR, Wu ZH.
World J Gastroenterol. 2006 Mar 7;12(9):1379-85. 

Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model.
Lin JY, Chen ML, Chiang BL, Lin BF.
Int Immunopharmacol. 2006 Feb;6(2):241-51.

Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages.
Woo CW, Man RY, Siow YL, Choy PC, Wan EW, Lau CS, O K.
Mol Cell Biochem. 2005 Jul;275(1-2):165-71. 

Antimicrobial, cytotoxic and antioxidant activity of selected basidiomycetes from Yemen.
Al-Fatimi M, Wurster M, Kreisel H, Lindequist U.
Pharmazie. 2005 Oct;60(10):776-80. 

Antioxidant and nitric oxide synthase activation properties of Ganoderma applanatum.
Acharya K, Yonzone P, Rai M, Rupa A.
Indian J Exp Biol. 2005 Oct;43(10):926-9. 

Effect of Ganoderma lucidum on the quality and functionality of Korean traditional rice wine, yakju.
Kim JH, Lee DH, Lee SH, Choi SY, Lee JS.
J Biosci Bioeng. 2004;97(1):24-8. 

Ganoderma lucidum mycelia enhance innate immunity by activating NF-kappaB.
Kuo MC, Weng CY, Ha CL, Wu MJ.
J Ethnopharmacol. 2006 Jan 16;103(2):217-22.

Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide.
Wachtel-Galor S, Choi SW, Benzie IF.
Redox Rep. 2005;10(3):145-9.

Manganese superoxide dismutase in pathogenic fungi: an issue with pathophysiological and phylogenetic involvements.
Fréalle E, Noël C, Viscogliosi E, Camus D, Dei-Cas E, Delhaes L.
FEMS Immunol Med Microbiol. 2005 Sep 1;45(3):411-22.

Antitumor activity and underlying mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma lucidum, in mice.
Gao Y, Gao H, Chan E, Tang W, Xu A, Yang H, Huang M, Lan J, Li X, Duan W, Xu C, Zhou S.
Immunol Invest. 2005;34(2):171-98. 

Formulation and in vitro/in vivo evaluation of combining DNA repair and immune enhancing nutritional supplements.
Pero RW, Amiri A, Sheng Y, Welther M, Rich M.
Phytomedicine. 2005 Apr;12(4):255-63.

New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
Kimura Y.
In Vivo. 2005 Jan-Feb;19(1):37-60.

Antioxidant activity of Ganoderma lucidum in acute ethanol-induced heart toxicity.
Wong KL, Chao HH, Chan P, Chang LP, Liu CF.
Phytother Res. 2004 Dec;18(12):1024-6.

Ganoderma total sterol (GS) and GS1 protect rat cerebral cortical neurons from hypoxia/reoxygenation injury.
Zhao HB, Wang SZ, He QH, Yuan L, Chen AF, Lin ZB.
Life Sci. 2005 Jan 14;76(9):1027-37.

Novel antioxidant peptides from fermented mushroom Ganoderma lucidum.
Sun J, He H, Xie BJ.
J Agric Food Chem. 2004 Oct 20;52(21):6646-52. 

Polysaccharide extract isolated from ganoderma lucidum protects rat cerebral cortical neurons from hypoxia/reoxygenation injury.
Zhao HB, Lin SQ, Liu JH, Lin ZB.
J Pharmacol Sci. 2004 Jun;95(2):294-8. 

[Activation of mouse macrophages by the alkali-extracted polysaccharide from spore of Ganoderma lucidum]
Tang QJ, Zhang JS, Pan YJ, Reutter W, Fan H.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2004 Mar;20(2):142-4.  

Selenium distribution in a Se-enriched mushroom species of the genus Ganoderma.
Zhao L, Zhao G, Zhao Z, Chen P, Tong J, Hu X.
J Agric Food Chem. 2004 Jun 16;52(12):3954-9. 

Biologically active compounds from Aphyllophorales (polypore) fungi.
Zjawiony JK.
J Nat Prod. 2004 Feb;67(2):300-10.

Ganoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study.
Wachtel-Galor S, Tomlinson B, Benzie IF.
Br J Nutr. 2004 Feb;91(2):263-9. 

Treatment of glomerular endothelial dysfunction in steroid-resistant nephrosis with Ganoderma lucidum, vitamins C, E and vasodilators.
Futrakul N, Boonyen M, Patumraj S, Siriviriyakul P, Tosukhowong P, Futrakul P.
Clin Hemorheol Microcirc. 2003;29(3-4):205-10. 

Anti-angiogenic and inhibitory activity on inducible nitric oxide production of the mushroom Ganoderma lucidum.
Song YS, Kim SH, Sa JH, Jin C, Lim CJ, Park EH.
J Ethnopharmacol. 2004 Jan;90(1):17-20.

Ganoderma lucidum ('Lingzhi'); acute and short-term biomarker response to supplementation.
Wachtel-Galor S, Szeto YT, Tomlinson B, Benzie IF.
Int J Food Sci Nutr. 2004 Feb;55(1):75-83. 

In vitro analysis of the properties of Beiqishen tea.
Blázovics A, Szentmihályi K, Lugasi A, Balázs A, Hagymási K, Bányai E, Then M, Rapavi E, Héthelyi E.
Nutrition. 2003 Oct;19(10):869-75.

In vitro and in vivo protective effect of Ganoderma lucidum polysaccharides on alloxan-induced pancreatic islets damage.
Zhang HN, He JH, Yuan L, Lin ZB.
Life Sci. 2003 Sep 19;73(18):2307-19. 

[Experimental study on cardiac protection and anti-oxidation effects of jisheng injection]
Zhang SQ, Shi XJ.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2003 Jun;23(6):455-7.  

[Antioxidant effect of Ganoderma polysaccharide peptide]
You YH, Lin ZB.
Yao Xue Xue Bao. 2003 Feb;38(2):85-8.

Assessment of membrane protection by traditional Chinese medicines using a flow cytometric technique: preliminary findings.
Chung WY, Yow CM, Benzie IF.
Redox Rep. 2003;8(1):31-3.

Antioxidant properties of several medicinal mushrooms.
Mau JL, Lin HC, Chen CC.
J Agric Food Chem. 2002 Oct 9;50(21):6072-7.

Protective effects of Ganoderma lucidum polysaccharides peptide on injury of macrophages induced by reactive oxygen species.
You YH, Lin ZB.
Acta Pharmacol Sin. 2002 Sep;23(9):787-91. 

Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice.
Zhang GL, Wang YH, Ni W, Teng HL, Lin ZB.
World J Gastroenterol. 2002 Aug;8(4):728-33. 

Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway.
Hsu MJ, Lee SS, Lin WW.
J Leukoc Biol. 2002 Jul;72(1):207-16. 

Evaluation of the hepatic and renal-protective effects of Ganoderma lucidum in mice.
Shieh YH, Liu CF, Huang YK, Yang JY, Wu IL, Lin CH, Li SC.
Am J Chin Med. 2001;29(3-4):501-7. 

Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum.
Lee JM, Kwon H, Jeong H, Lee JW, Lee SY, Baek SJ, Surh YJ.
Phytother Res. 2001 May;15(3):245-9. 

Triterpene antioxidants from ganoderma lucidum.
Zhu M, Chang Q, Wong LK, Chong FS, Li RC.
Phytother Res. 1999 Sep;13(6):529-31. 

Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.
Kim KC, Kim IG.
Int J Mol Med. 1999 Sep;4(3):273-7. 

Purification and characterization of manganese superoxide dismutase from Ganoderma microsporum.
Pan SM, Ye JS, Hseu RS.
Biochem Mol Biol Int. 1997 Aug;42(5):1035-43. 

Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction.
Park EJ, Ko G, Kim J, Sohn DH.
Biol Pharm Bull. 1997 Apr;20(4):417-20. Erratum in: Biol Pharm Bull 1998 Jun;21(6):649.       : 9145221 [PubMed - indexed for MEDLINE]Related citations

Radical scavenger and antihepatotoxic activity of Ganoderma formosanum, Ganoderma lucidum and Ganoderma neo-japonicum.
Lin JM, Lin CC, Chen MF, Ujiie T, Takada A.
J Ethnopharmacol. 1995 Jun 23;47(1):33-41. 

Trial of a new medium-term model using benzo(a)pyrene induced lung tumor in newborn mice.
Yun TK, Kim SH, Lee YS.
Anticancer Res. 1995 May-Jun;15(3):839-45. 

Recent advances in studies on traditional Chinese anti-aging materia medica.
Chen K, Li C.
J Tradit Chin Med. 1993 Sep;13(3):223-6, contd.

Zhang J, Tang Q, Zhou C, Jia W, Da Silva L, Nguyen LD, Reutter W, Fan H.
Ganoderma atrum polysaccharide attenuates oxidative stress induced by d-galactose in mouse brain.
Li WJ, Nie SP, Xie MY, Yu Q, Chen Y, He M.
Life Sci. 2011 Apr 11;88(15-16):713-8. Epub 2011 Feb 18.

Comparison of Antioxidant Capacities of Ganoderma lucidum (Curtis) P. Karst and Funalia trogii (Berk.)
Yegenoglu H, Aslim B, Oke F.
J Med Food. 2011 Feb 11.

GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response.
Zhang J, Tang Q, Zhou C, Jia W, Da Silva L, Nguyen LD, Reutter W, Fan H.
Life Sci. 2010 Nov 20;87(19-22):628-37. Epub 2010 Oct 1.

Medicinal and edible lignicolous fungi as natural sources of antioxidative and antibacterial agents.
Karaman M, Jovin E, Malbasa R, Matavuly M,
Popović M. Phytother Res. 2010 Oct;24(10):1473-81.
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